Aerospace Engineering and Engineering Mechanics

Research Output 1954 2019

2019
2 Citations (Scopus)

A Computational Cardiac Model for the Adaptation to Pulmonary Arterial Hypertension in the Rat

Avazmohammadi, R., Mendiola, E. A., Soares, J. S., Li, D. S., Chen, Z., Merchant, S., Hsu, E. W., Vanderslice, P., Dixon, R. A. F. & Sacks, M. S., Jan 15 2019, In : Annals of Biomedical Engineering. 47, 1, p. 138-153 16 p.

Research output: Contribution to journalArticle

Rats
Fibers
Collagen
Stiffness
Geometry

A Contemporary Look at Biomechanical Models of Myocardium

Avazmohammadi, R., Soares, J. S., Li, D. S., Raut, S. S., Gorman, R. C. & Sacks, M. S., Jan 1 2019, In : Annual Review of Biomedical Engineering. 21, p. 417-442 26 p.

Research output: Contribution to journalReview article

Myocardium
Constitutive models
Therapeutics
3 Citations (Scopus)

A material modeling approach for the effective response of planar soft tissues for efficient computational simulations

Zhang, W., Zakerzadeh, R., Zhang, W. & Sacks, M. S., Jan 1 2019, In : Journal of the Mechanical Behavior of Biomedical Materials. 89, p. 168-198 31 p.

Research output: Contribution to journalArticle

Constitutive models
Tissue
Parameter estimation
Computational efficiency
Anisotropy

Analyzing valve interstitial cell mechanics and geometry with spatial statistics

Lejeune, E. & Sacks, M. S., Aug 27 2019, In : Journal of Biomechanics. 93, p. 159-166 8 p.

Research output: Contribution to journalArticle

Mechanics
Atomic force microscopy
Statistics
Geometry
Autocorrelation

A preliminary study of the local biomechanical environment of liver tumors in vivo

Ma, S., Zhu, M., Xia, X., Guo, L., Genin, G. M., Sacks, M. S., Gao, M., Mutic, S., Hu, Y., Hu, C. H. & Feng, Y., Apr 1 2019, In : Medical Physics. 46, 4, p. 1728-1739 12 p.

Research output: Contribution to journalArticle

Liver
Neoplasms
Hemangioma
Hepatocellular Carcinoma
Tumor Biomarkers
2 Citations (Scopus)

Development of a Functionally Equivalent Model of the Mitral Valve Chordae Tendineae Through Topology Optimization

Khalighi, A. H., Rego, B. V., Drach, A., Gorman, R. C., Gorman, J. H. & Sacks, M. S., Jan 15 2019, In : Annals of Biomedical Engineering. 47, 1, p. 60-74 15 p.

Research output: Contribution to journalArticle

Shape optimization
Geometry
Tensors
Redundancy
Muscle
2 Citations (Scopus)

Non-Destructive Reflectance Mapping of Collagen Fiber Alignment in Heart Valve Leaflets

Goth, W., Potter, S., Allen, A. C. B., Zoldan, J., Sacks, M. S. & Tunnell, J., May 15 2019, In : Annals of Biomedical Engineering. 47, 5, p. 1250-1264 15 p.

Research output: Contribution to journalArticle

Collagen
Fibers
Tissue
Imaging techniques
Fiber reinforced materials
1 Citation (Scopus)

On the Simulation of Mitral Valve Function in Health, Disease, and Treatment

Sacks, M. S., Drach, A., Lee, C. H., Khalighi, A. H., Rego, B. V., Zhang, W., Ayoub, S., Yoganathan, A. P., Gorman, R. C. & Gorman, J. H., Jul 1 2019, In : Journal of Biomechanical Engineering. 141, 7, 070804.

Research output: Contribution to journalArticle

Mitral Valve
Repair
Blood
Mitral Valve Insufficiency
Health

Quantifying heart valve interstitial cell contractile state using highly tunable poly(ethylene glycol) hydrogels

Khang, A., Gonzalez Rodriguez, A., Schroeder, M. E., Sansom, J., Lejeune, E., Anseth, K. S. & Sacks, M. S., Sep 15 2019, In : Acta Biomaterialia. 96, p. 354-367 14 p.

Research output: Contribution to journalArticle

Hydrogels
Ethylene Glycol
Heart Valves
Polyethylene glycols
Gels

Regional biomechanical imaging of liver cancer cells

Pei, W., Chen, J., Wang, C., Qiu, S., Zeng, J., Gao, M., Zhou, B., Li, D., Sacks, M. S., Han, L., Shan, H., Hu, W., Zhou, G. & Feng, Y., Jan 1 2019, In : Journal of Cancer. 10, 19, p. 4481-4487 7 p.

Research output: Contribution to journalArticle

Open Access
Liver Neoplasms
Atomic Force Microscopy
Normal Distribution
Hep G2 Cells
Cytoskeleton
2018
12 Citations (Scopus)
Multiresolution Modeling
Computational efficiency
Mitral Valve
Computational Efficiency
Pipelines
14 Citations (Scopus)

A framework for designing patient-specific bioprosthetic heart valves using immersogeometric fluid–structure interaction analysis

Xu, F., Morganti, S., Zakerzadeh, R., Kamensky, D., Auricchio, F., Reali, A., Hughes, T. J. R., Sacks, M. S. & Hsu, M. C., Apr 2018, In : International Journal for Numerical Methods in Biomedical Engineering. 34, 4, e2938.

Research output: Contribution to journalArticle

Heart Valves
Medical Image
Interaction
Equipment Design
Roots
4 Citations (Scopus)

An anisotropic constitutive model for immersogeometric fluid–structure interaction analysis of bioprosthetic heart valves

Wu, M. C. H., Zakerzadeh, R., Kamensky, D., Kiendl, J., Sacks, M. S. & Hsu, M. C., Jun 6 2018, In : Journal of Biomechanics. 74, p. 23-31 9 p.

Research output: Contribution to journalArticle

Heart Valves
Constitutive models
Tissue
Anisotropy
Blood
3 Citations (Scopus)

An integrated inverse model-experimental approach to determine soft tissue three-dimensional constitutive parameters: Application to post-infarcted myocardium

Avazmohammadi, R., Li, D. S., Leahy, T., Shih, E., Soares, J. S., Gorman, J. H., Gorman, R. C. & Sacks, M. S., Jan 1 2018, In : Biomechanics and Modeling in Mechanobiology. 17, 1, p. 31-53 23 p.

Research output: Contribution to journalArticle

Strain Energy Density
Inverse Model
Myocardium
Soft Tissue
Integrated Model
3 Citations (Scopus)

A noninvasive method for the determination of in vivo mitral valve leaflet strains

Rego, B. V., Khalighi, A. H., Drach, A., Lai, E. K., Pouch, A. M., Gorman, R. C., Gorman, J. H. & Sacks, M. S., Dec 1 2018, In : International Journal for Numerical Methods in Biomedical Engineering. 34, 12, e3142.

Research output: Contribution to journalArticle

Mitral Valve
Fiducial Markers
Container closures
Echocardiography
Closed
2 Citations (Scopus)

A Novel Small-Specimen Planar Biaxial Testing System with Full In-Plane Deformation Control

Potter, S., Graves, J., Drach, B., Leahy, T., Hammel, C., Feng, Y., Baker, A. & Sacks, M. S., May 1 2018, In : Journal of Biomechanical Engineering. 140, 5, 51001.

Research output: Contribution to journalArticle

Tissue
Equipment and Supplies
Testing
Constitutive models
Tensors
6 Citations (Scopus)

Multi-resolution geometric modeling of the mitral heart valve leaflets

Khalighi, A. H., Drach, A., Gorman, R. C., Gorman, J. H. & Sacks, M. S., Apr 1 2018, In : Biomechanics and Modeling in Mechanobiology. 17, 2, p. 351-366 16 p.

Research output: Contribution to journalArticle

Multiresolution Modeling
Geometric Modeling
Heart Valves
Mitral Valve
Geometry
6 Citations (Scopus)

Perspectives on Sharing Models and Related Resources in Computational Biomechanics Research

Erdemir, A., Hunter, P. J., Holzapfel, G. A., Loew, L. M., Middleton, J., Jacobs, C. R., Nithiarasu, P., Löhner, R., Wei, G., Winkelstein, B. A., Barocas, V. H., Guilak, F., Ku, J. P., Hicks, J. L., Delp, S. L., Sacks, M., Weiss, J. A., Ateshian, G. A., Maas, S. A., McCulloch, A. D. & 1 others, Peng, G. C. Y., Feb 1 2018, In : Journal of Biomechanical Engineering. 140, 2, 024701.

Research output: Contribution to journalReview article

Open Access
Biomechanics
Biomechanical Phenomena
Research
Software
Biological Phenomena
3 Citations (Scopus)

Porphyrin-based SOD mimic MnTnBuOE-2-PyP5+ inhibits mechanisms of aortic valve remodeling in human and murine models of aortic valve sclerosis

Anselmo, W., Branchetti, E., Grau, J. B., Li, G., Ayoub, S., Lai, E. K., Rioux, N., Tovmasyan, A., Fortier, J. H., Sacks, M. S., Batinic-Haberle, I., Hazen, S. L., Levy, R. J. & Ferrari, G., Oct 1 2018, In : Journal of the American Heart Association. 7, 20, e007861.

Research output: Contribution to journalArticle

Open Access
Porphyrins
Sclerosis
Aortic Valve
Superoxide Dismutase
Extracellular Matrix
6 Citations (Scopus)

Serotonin receptor 2B signaling with interstitial cell activation and leaflet remodeling in degenerative mitral regurgitation

Driesbaugh, K. H., Branchetti, E., Grau, J. B., Keeney, S. J., Glass, K., Oyama, M. A., Rioux, N., Ayoub, S., Sacks, M. S., Quackenbush, J., Levy, R. J. & Ferrari, G., Feb 1 2018, In : Journal of Molecular and Cellular Cardiology. 115, p. 94-103 10 p.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT2B
Mitral Valve Prolapse
Mitral Valve Insufficiency
Mitral Valve
Angiotensin II
6 Citations (Scopus)

The Three-Dimensional Microenvironment of the Mitral Valve: Insights into the Effects of Physiological Loads

Ayoub, S., Tsai, K. C., Khalighi, A. H. & Sacks, M. S., Aug 1 2018, In : Cellular and Molecular Bioengineering. 11, 4, p. 291-306 16 p.

Research output: Contribution to journalArticle

Elastin
Mitral Valve
Collagen
Three-dimensional
Fibers

Virtual heart guides cardiac ablation

Sacks, M. S., Oct 1 2018, In : Nature biomedical engineering. 2, 10, p. 711-712 2 p.

Research output: Contribution to journalComment/debate

Ablation
2017
2 Citations (Scopus)

ACCURACY AND CONVERGENCE OF FINITE ELEMENT/GALERKIN APPROXIMATIONS OF TIME-DEPENDENT PROBLEMS WITH EMPHASIS ON DIFFUSION.

Wellford, L. C. & Oden, J. T., Jan 1 2017, p. 31-54. 24 p.

Research output: Contribution to conferencePaper

17 Citations (Scopus)

A functionally graded material model for the transmural stress distribution of the aortic valve leaflet

Rego, B. V. & Sacks, M. S., Mar 21 2017, In : Journal of Biomechanics. 54, p. 88-95 8 p.

Research output: Contribution to journalArticle

Functionally graded materials
Aortic Valve
Stress concentration
Extracellular Matrix
Diastole
6 Citations (Scopus)

A mathematical model for the determination of forming tissue moduli in needled-nonwoven scaffolds

Soares, J. S., Zhang, W. & Sacks, M. S., Mar 15 2017, In : Acta Biomaterialia. 51, p. 220-236 17 p.

Research output: Contribution to journalArticle

Scaffolds (biology)
Theoretical Models
Scaffolds
Tissue
Mathematical models
64 Citations (Scopus)
Advection
Navier Stokes equations

Analysis of gravity offshore structure foundations.

Prevost, J. H., Hughes, T. J. & Cohen, M. F., Jan 1 2017, In : J. PET. TECHNOL.. 32, 2 , Feb. 1980, p. 199-209 11 p.

Research output: Contribution to journalArticle

Offshore structures
Gravitation
Soils
Gravity
Interaction

ANALYSIS OF GRAVITY OFFSHORE STRUCTURE FOUNDATIONS SUBJECTED TO CYCLIC WAVE LOADING.

Prevost, J. H. & Hughes, T. J. R., Jan 1 2017, In : Proceedings of the Annual Offshore Technology Conference. 3, p. 1809-1818 10 p.

Research output: Contribution to journalConference article

Offshore structures
Gravitation
Soils
Analytical models
Clay
17 Citations (Scopus)

A novel constitutive model for passive right ventricular myocardium: evidence for myofiber–collagen fiber mechanical coupling

Avazmohammadi, R., Hill, M. R., Simon, M. A., Zhang, W. & Sacks, M. S., Apr 1 2017, In : Biomechanics and Modeling in Mechanobiology. 16, 2, p. 561-581 21 p.

Research output: Contribution to journalArticle

Myocardium
Constitutive Model
Constitutive models
Collagen
Fiber

A review on the biomechanical effects of fatigue on the porcine bioprosthetic heart valve

Sacks, M. S., Jan 1 2017, In : Journal of Long-Term Effects of Medical Implants. 27, 2-4, p. 181-197 17 p.

Research output: Contribution to journalReview article

Heart Valves
Collagen
Fatigue
Swine
Fatigue of materials
4 Citations (Scopus)

Biomechanical and hemodynamic measures of right ventricular diastolic function: Translating tissue biomechanics to clinical relevance

Jang, S., Vanderpool, R. R., Avazmohammadi, R., Lapshin, E., Bachman, T. N., Sacks, M. S. & Simon, M. A., Sep 1 2017, In : Journal of the American Heart Association. 6, 9, e006084.

Research output: Contribution to journalArticle

Open Access
Right Ventricular Function
Biomechanical Phenomena
Hemodynamics
Ventricular Pressure
Heart Ventricles
5 Citations (Scopus)

Computational methods for the aortic heart valve and its replacements

Zakerzadeh, R., Hsu, M. C. & Sacks, M. S., Nov 2 2017, In : Expert Review of Medical Devices. 14, 11, p. 849-866 18 p.

Research output: Contribution to journalReview article

Heart Valves
Computational methods
Aortic Valve
Prosthetics
Heart Valve Prosthesis
4 Citations (Scopus)

Editorial: On the need for multi-scale geometric modeling of the mitral heart valve

Sacks, M. S., Khalighi, A., Rego, B., Ayoub, S. & Drach, A., Jan 1 2017, In : Healthcare Technology Letters. 4, 5, 1 p.

Research output: Contribution to journalEditorial

Open Access
Heart Valves
Mitral Valve
16 Citations (Scopus)

Ex Vivo Methods for Informing Computational Models of the Mitral Valve

Bloodworth, C. H., Pierce, E. L., Easley, T. F., Drach, A., Khalighi, A. H., Toma, M., Jensen, M. O., Sacks, M. S. & Yoganathan, A. P., Feb 1 2017, In : Annals of Biomedical Engineering. 45, 2, p. 496-507 12 p.

Research output: Contribution to journalArticle

Tomography
Repair
Imaging techniques
Geometry
Simulators
17 Citations (Scopus)

Fixation of Bovine Pericardium-Based Tissue Biomaterial with Irreversible Chemistry Improves Biochemical and Biomechanical Properties

Tam, H., Zhang, W., Infante, D., Parchment, N., Sacks, M. S. & Vyavahare, N., Apr 1 2017, In : Journal of Cardiovascular Translational Research. 10, 2, p. 194-205 12 p.

Research output: Contribution to journalArticle

Pericardium
Biocompatible Materials
Glutaral
Heart Valves
Carbodiimides
24 Citations (Scopus)

Immersogeometric cardiovascular fluid–structure interaction analysis with divergence-conforming B-splines

Kamensky, D., Hsu, M. C., Yu, Y., Evans, J. A., Sacks, M. S. & Hughes, T. J. R., Feb 1 2017, In : Computer Methods in Applied Mechanics and Engineering. 314, p. 408-472 65 p.

Research output: Contribution to journalArticle

splines
Splines
divergence
heart valves
conservation

Interpreting fiber structure from polarization dependent optical anisotropy

Goth, W., Sacks, M. S. & Tunnell, J., Jan 1 2017, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XV. Farkas, D. L., Nicolau, D. V. & Leif, R. C. (eds.). SPIE, 100680P. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10068).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Optical anisotropy
Anisotropy
Polarization
anisotropy
Fiber reinforced materials
4 Citations (Scopus)

Layered Elastomeric Fibrous Scaffolds: An In-Silico Study of the Achievable Range of Mechanical Behaviors

Carleton, J. B., Rodin, G. J. & Sacks, M. S., Nov 13 2017, In : ACS Biomaterials Science and Engineering. 3, 11, p. 2907-2921 15 p.

Research output: Contribution to journalArticle

Scaffolds
Biocompatible Materials
Geometry
Tissue
Biomaterials

METHOD FOR HANDLING COAST ARCS IN LOW-THRUST INTERPLANETARY TRAJECTORY OPTIMIZATION.

O'Neill, P. M. & Fowler, W. T., Jan 1 2017, In : Am Astron Soc/AIAA Astrodyn Spec Conf.

Research output: Contribution to journalArticle

Coastal zones
Trajectories
Switching functions
Extrapolation
Earth (planet)
15 Citations (Scopus)

Mitral Valve Chordae Tendineae: Topological and Geometrical Characterization

Khalighi, A. H., Drach, A., Bloodworth, C. H., Pierce, E. L., Yoganathan, A. P., Gorman, R. C., Gorman, J. H. & Sacks, M. S., Feb 1 2017, In : Annals of Biomedical Engineering. 45, 2, p. 378-393 16 p.

Research output: Contribution to journalArticle

Geometry
Muscle
Repair
Bearings (structural)
Binary trees
2 Citations (Scopus)

Modeling of myocardium compressibility and its impact in computational simulations of the healthy and infarcted heart

Soares, J. S., Li, D. S., Lai, E., Gorman, J. H., Gorman, R. C. & Sacks, M. S., Jan 1 2017, Functional Imaging and Modelling of the Heart - 9th International Conference, FIMH 2017, Proceedings. Pop, M. & Wright, G. A. (eds.). Springer Verlag, p. 493-501 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10263 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Computational Simulation
Myocardium
Compressibility
Cardiac
Modeling
9 Citations (Scopus)
Tissue
Geometry
Collagen
Glutaral
Fibers

NEW FINITE ELEMENT FOR PLATE BENDING ANALYSIS.

Hughes, T. J. & Taylor, R. L., Jan 1 2017.

Research output: Contribution to conferencePaper

Mindlin plates
6 Citations (Scopus)

On the Functional Role of Valve Interstitial Cell Stress Fibers: A Continuum Modeling Approach

Sakamoto, Y., Buchanan, R. M., Sanchez-Adams, J., Guilak, F. & Sacks, M. S., Feb 1 2017, In : Journal of Biomechanical Engineering. 139, 2, 021002.

Research output: Contribution to journalArticle

Stress Fibers
Fibers
Strain rate
Actins
Chemical activation
8 Citations (Scopus)

On the in vivo function of the mitral heart valve leaflet: insights into tissue–interstitial cell biomechanical coupling

Lee, C. H., Zhang, W., Feaver, K., Gorman, R. C., Gorman, J. H. & Sacks, M. S., Oct 1 2017, In : Biomechanics and Modeling in Mechanobiology. 16, 5, p. 1613-1632 20 p.

Research output: Contribution to journalArticle

Heart Valves
Mitral Valve
Tissue
Cell
Kinematics

On the 'slip-on' buckle arrestor for offshore pipelines.

Kyriakides, S. & Babcock, C. D., Jan 1 2017, In : TRANS. ASME J. PRESSURE VESSEL TECHNOL.. 102, 2 , May 1980, p. 188-193 6 p.

Research output: Contribution to journalArticle

Offshore pipelines
Pipelines
Pipe

OPTIMAL RUNGE-KUTTA METHODS.

Hull, D. G. & Bettis, D. G., Jan 1 2017, In : Am Astron Soc/AIAA Astrodyn Spec Conf.

Research output: Contribution to journalArticle

Runge Kutta methods
Function evaluation
10 Citations (Scopus)

Regulation of valve interstitial cell homeostasis by mechanical deformation: Implications for heart valve disease and surgical repair

Ayoub, S., Lee, C. H., Driesbaugh, K. H., Anselmo, W., Hughes, C. T., Ferrari, G., Gorman, R. C., Gorman, J. H. & Sacks, M. S., Oct 1 2017, In : Journal of the Royal Society Interface. 14, 135, 20170580.

Research output: Contribution to journalArticle

Open Access
Heart Valve Diseases
Homeostasis
Repair
Tissue
Mitral Valve

SENSITIVITY ANALYSIS OF SHORT-ARC STATION COORDINATE DETERMINATIONS FROM RANGE DATA.

Schutz, B. E. & Tapley, B. D., Jan 1 2017, In : Am Astron Soc/AIAA Astrodyn Spec Conf.

Research output: Contribution to journalArticle

Sensitivity analysis
Satellites
Drag
Earth (planet)
Geometry

SHELL STRUCTURES AND CLIMATIC INFLUENCES.

Candela, F., Davenport, A. G., Finn, W. D. L., Gerwick, B. C., Naghdi, P. M., Oden, J. T., Buchert, K., McQuigg, J., Benjamin, N., Johnson, S., LeDuc, S., Greenwald, T. & Keresztesy, L. O., Jan 1 2017.

Research output: Contribution to conferencePaper

Roofs
Atmospheric humidity
Membranes
Wind effects
Ocean structures