Aerospace Engineering and Engineering Mechanics

Research Output 1954 2019

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2019
2 Citations (Scopus)

A Computational Cardiac Model for the Adaptation to Pulmonary Arterial Hypertension in the Rat

Avazmohammadi, R., Mendiola, E. A., Soares, J. S., Li, D. S., Chen, Z., Merchant, S., Hsu, E. W., Vanderslice, P., Dixon, R. A. F. & Sacks, M. S., Jan 15 2019, In : Annals of Biomedical Engineering. 47, 1, p. 138-153 16 p.

Research output: Contribution to journalArticle

Rats
Fibers
Collagen
Stiffness
Geometry
3 Citations (Scopus)

A material modeling approach for the effective response of planar soft tissues for efficient computational simulations

Zhang, W., Zakerzadeh, R., Zhang, W. & Sacks, M. S., Jan 1 2019, In : Journal of the Mechanical Behavior of Biomedical Materials. 89, p. 168-198 31 p.

Research output: Contribution to journalArticle

Constitutive models
Tissue
Parameter estimation
Computational efficiency
Anisotropy

Analyzing valve interstitial cell mechanics and geometry with spatial statistics

Lejeune, E. & Sacks, M. S., Aug 27 2019, In : Journal of Biomechanics. 93, p. 159-166 8 p.

Research output: Contribution to journalArticle

Mechanics
Atomic force microscopy
Statistics
Geometry
Autocorrelation

A preliminary study of the local biomechanical environment of liver tumors in vivo

Ma, S., Zhu, M., Xia, X., Guo, L., Genin, G. M., Sacks, M. S., Gao, M., Mutic, S., Hu, Y., Hu, C. H. & Feng, Y., Apr 1 2019, In : Medical Physics. 46, 4, p. 1728-1739 12 p.

Research output: Contribution to journalArticle

Liver
Neoplasms
Hemangioma
Hepatocellular Carcinoma
Tumor Biomarkers
2 Citations (Scopus)

Development of a Functionally Equivalent Model of the Mitral Valve Chordae Tendineae Through Topology Optimization

Khalighi, A. H., Rego, B. V., Drach, A., Gorman, R. C., Gorman, J. H. & Sacks, M. S., Jan 15 2019, In : Annals of Biomedical Engineering. 47, 1, p. 60-74 15 p.

Research output: Contribution to journalArticle

Shape optimization
Geometry
Tensors
Redundancy
Muscle
2 Citations (Scopus)

Non-Destructive Reflectance Mapping of Collagen Fiber Alignment in Heart Valve Leaflets

Goth, W., Potter, S., Allen, A. C. B., Zoldan, J., Sacks, M. S. & Tunnell, J., May 15 2019, In : Annals of Biomedical Engineering. 47, 5, p. 1250-1264 15 p.

Research output: Contribution to journalArticle

Collagen
Fibers
Tissue
Imaging techniques
Fiber reinforced materials
1 Citation (Scopus)

On the Simulation of Mitral Valve Function in Health, Disease, and Treatment

Sacks, M. S., Drach, A., Lee, C. H., Khalighi, A. H., Rego, B. V., Zhang, W., Ayoub, S., Yoganathan, A. P., Gorman, R. C. & Gorman, J. H., Jul 1 2019, In : Journal of Biomechanical Engineering. 141, 7, 070804.

Research output: Contribution to journalArticle

Mitral Valve
Repair
Blood
Mitral Valve Insufficiency
Health

Quantifying heart valve interstitial cell contractile state using highly tunable poly(ethylene glycol) hydrogels

Khang, A., Gonzalez Rodriguez, A., Schroeder, M. E., Sansom, J., Lejeune, E., Anseth, K. S. & Sacks, M. S., Sep 15 2019, In : Acta Biomaterialia. 96, p. 354-367 14 p.

Research output: Contribution to journalArticle

Hydrogels
Ethylene Glycol
Heart Valves
Polyethylene glycols
Gels

Regional biomechanical imaging of liver cancer cells

Pei, W., Chen, J., Wang, C., Qiu, S., Zeng, J., Gao, M., Zhou, B., Li, D., Sacks, M. S., Han, L., Shan, H., Hu, W., Zhou, G. & Feng, Y., Jan 1 2019, In : Journal of Cancer. 10, 19, p. 4481-4487 7 p.

Research output: Contribution to journalArticle

Open Access
Liver Neoplasms
Atomic Force Microscopy
Normal Distribution
Hep G2 Cells
Cytoskeleton
2018
12 Citations (Scopus)
Multiresolution Modeling
Computational efficiency
Mitral Valve
Computational Efficiency
Pipelines
14 Citations (Scopus)

A framework for designing patient-specific bioprosthetic heart valves using immersogeometric fluid–structure interaction analysis

Xu, F., Morganti, S., Zakerzadeh, R., Kamensky, D., Auricchio, F., Reali, A., Hughes, T. J. R., Sacks, M. S. & Hsu, M. C., Apr 2018, In : International Journal for Numerical Methods in Biomedical Engineering. 34, 4, e2938.

Research output: Contribution to journalArticle

Heart Valves
Medical Image
Interaction
Equipment Design
Roots
4 Citations (Scopus)

An anisotropic constitutive model for immersogeometric fluid–structure interaction analysis of bioprosthetic heart valves

Wu, M. C. H., Zakerzadeh, R., Kamensky, D., Kiendl, J., Sacks, M. S. & Hsu, M. C., Jun 6 2018, In : Journal of Biomechanics. 74, p. 23-31 9 p.

Research output: Contribution to journalArticle

Heart Valves
Constitutive models
Tissue
Anisotropy
Blood
3 Citations (Scopus)

An integrated inverse model-experimental approach to determine soft tissue three-dimensional constitutive parameters: Application to post-infarcted myocardium

Avazmohammadi, R., Li, D. S., Leahy, T., Shih, E., Soares, J. S., Gorman, J. H., Gorman, R. C. & Sacks, M. S., Jan 1 2018, In : Biomechanics and Modeling in Mechanobiology. 17, 1, p. 31-53 23 p.

Research output: Contribution to journalArticle

Strain Energy Density
Inverse Model
Myocardium
Soft Tissue
Integrated Model
3 Citations (Scopus)

A noninvasive method for the determination of in vivo mitral valve leaflet strains

Rego, B. V., Khalighi, A. H., Drach, A., Lai, E. K., Pouch, A. M., Gorman, R. C., Gorman, J. H. & Sacks, M. S., Dec 1 2018, In : International Journal for Numerical Methods in Biomedical Engineering. 34, 12, e3142.

Research output: Contribution to journalArticle

Mitral Valve
Fiducial Markers
Container closures
Echocardiography
Closed
2 Citations (Scopus)

A Novel Small-Specimen Planar Biaxial Testing System with Full In-Plane Deformation Control

Potter, S., Graves, J., Drach, B., Leahy, T., Hammel, C., Feng, Y., Baker, A. & Sacks, M. S., May 1 2018, In : Journal of Biomechanical Engineering. 140, 5, 51001.

Research output: Contribution to journalArticle

Tissue
Equipment and Supplies
Testing
Constitutive models
Tensors
6 Citations (Scopus)

Multi-resolution geometric modeling of the mitral heart valve leaflets

Khalighi, A. H., Drach, A., Gorman, R. C., Gorman, J. H. & Sacks, M. S., Apr 1 2018, In : Biomechanics and Modeling in Mechanobiology. 17, 2, p. 351-366 16 p.

Research output: Contribution to journalArticle

Multiresolution Modeling
Geometric Modeling
Heart Valves
Mitral Valve
Geometry
3 Citations (Scopus)

Porphyrin-based SOD mimic MnTnBuOE-2-PyP5+ inhibits mechanisms of aortic valve remodeling in human and murine models of aortic valve sclerosis

Anselmo, W., Branchetti, E., Grau, J. B., Li, G., Ayoub, S., Lai, E. K., Rioux, N., Tovmasyan, A., Fortier, J. H., Sacks, M. S., Batinic-Haberle, I., Hazen, S. L., Levy, R. J. & Ferrari, G., Oct 1 2018, In : Journal of the American Heart Association. 7, 20, e007861.

Research output: Contribution to journalArticle

Open Access
Porphyrins
Sclerosis
Aortic Valve
Superoxide Dismutase
Extracellular Matrix
6 Citations (Scopus)

Serotonin receptor 2B signaling with interstitial cell activation and leaflet remodeling in degenerative mitral regurgitation

Driesbaugh, K. H., Branchetti, E., Grau, J. B., Keeney, S. J., Glass, K., Oyama, M. A., Rioux, N., Ayoub, S., Sacks, M. S., Quackenbush, J., Levy, R. J. & Ferrari, G., Feb 1 2018, In : Journal of Molecular and Cellular Cardiology. 115, p. 94-103 10 p.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT2B
Mitral Valve Prolapse
Mitral Valve Insufficiency
Mitral Valve
Angiotensin II
6 Citations (Scopus)

The Three-Dimensional Microenvironment of the Mitral Valve: Insights into the Effects of Physiological Loads

Ayoub, S., Tsai, K. C., Khalighi, A. H. & Sacks, M. S., Aug 1 2018, In : Cellular and Molecular Bioengineering. 11, 4, p. 291-306 16 p.

Research output: Contribution to journalArticle

Elastin
Mitral Valve
Collagen
Three-dimensional
Fibers
2017
17 Citations (Scopus)

A functionally graded material model for the transmural stress distribution of the aortic valve leaflet

Rego, B. V. & Sacks, M. S., Mar 21 2017, In : Journal of Biomechanics. 54, p. 88-95 8 p.

Research output: Contribution to journalArticle

Functionally graded materials
Aortic Valve
Stress concentration
Extracellular Matrix
Diastole
6 Citations (Scopus)

A mathematical model for the determination of forming tissue moduli in needled-nonwoven scaffolds

Soares, J. S., Zhang, W. & Sacks, M. S., Mar 15 2017, In : Acta Biomaterialia. 51, p. 220-236 17 p.

Research output: Contribution to journalArticle

Scaffolds (biology)
Theoretical Models
Scaffolds
Tissue
Mathematical models
64 Citations (Scopus)
Advection
Navier Stokes equations

Analysis of gravity offshore structure foundations.

Prevost, J. H., Hughes, T. J. & Cohen, M. F., Jan 1 2017, In : J. PET. TECHNOL.. 32, 2 , Feb. 1980, p. 199-209 11 p.

Research output: Contribution to journalArticle

Offshore structures
Gravitation
Soils
Gravity
Interaction
17 Citations (Scopus)

A novel constitutive model for passive right ventricular myocardium: evidence for myofiber–collagen fiber mechanical coupling

Avazmohammadi, R., Hill, M. R., Simon, M. A., Zhang, W. & Sacks, M. S., Apr 1 2017, In : Biomechanics and Modeling in Mechanobiology. 16, 2, p. 561-581 21 p.

Research output: Contribution to journalArticle

Myocardium
Constitutive Model
Constitutive models
Collagen
Fiber
4 Citations (Scopus)

Biomechanical and hemodynamic measures of right ventricular diastolic function: Translating tissue biomechanics to clinical relevance

Jang, S., Vanderpool, R. R., Avazmohammadi, R., Lapshin, E., Bachman, T. N., Sacks, M. S. & Simon, M. A., Sep 1 2017, In : Journal of the American Heart Association. 6, 9, e006084.

Research output: Contribution to journalArticle

Open Access
Right Ventricular Function
Biomechanical Phenomena
Hemodynamics
Ventricular Pressure
Heart Ventricles
16 Citations (Scopus)

Ex Vivo Methods for Informing Computational Models of the Mitral Valve

Bloodworth, C. H., Pierce, E. L., Easley, T. F., Drach, A., Khalighi, A. H., Toma, M., Jensen, M. O., Sacks, M. S. & Yoganathan, A. P., Feb 1 2017, In : Annals of Biomedical Engineering. 45, 2, p. 496-507 12 p.

Research output: Contribution to journalArticle

Tomography
Repair
Imaging techniques
Geometry
Simulators
17 Citations (Scopus)

Fixation of Bovine Pericardium-Based Tissue Biomaterial with Irreversible Chemistry Improves Biochemical and Biomechanical Properties

Tam, H., Zhang, W., Infante, D., Parchment, N., Sacks, M. S. & Vyavahare, N., Apr 1 2017, In : Journal of Cardiovascular Translational Research. 10, 2, p. 194-205 12 p.

Research output: Contribution to journalArticle

Pericardium
Biocompatible Materials
Glutaral
Heart Valves
Carbodiimides
24 Citations (Scopus)

Immersogeometric cardiovascular fluid–structure interaction analysis with divergence-conforming B-splines

Kamensky, D., Hsu, M. C., Yu, Y., Evans, J. A., Sacks, M. S. & Hughes, T. J. R., Feb 1 2017, In : Computer Methods in Applied Mechanics and Engineering. 314, p. 408-472 65 p.

Research output: Contribution to journalArticle

splines
Splines
divergence
heart valves
conservation
4 Citations (Scopus)

Layered Elastomeric Fibrous Scaffolds: An In-Silico Study of the Achievable Range of Mechanical Behaviors

Carleton, J. B., Rodin, G. J. & Sacks, M. S., Nov 13 2017, In : ACS Biomaterials Science and Engineering. 3, 11, p. 2907-2921 15 p.

Research output: Contribution to journalArticle

Scaffolds
Biocompatible Materials
Geometry
Tissue
Biomaterials

METHOD FOR HANDLING COAST ARCS IN LOW-THRUST INTERPLANETARY TRAJECTORY OPTIMIZATION.

O'Neill, P. M. & Fowler, W. T., Jan 1 2017, In : Am Astron Soc/AIAA Astrodyn Spec Conf.

Research output: Contribution to journalArticle

Coastal zones
Trajectories
Switching functions
Extrapolation
Earth (planet)
15 Citations (Scopus)

Mitral Valve Chordae Tendineae: Topological and Geometrical Characterization

Khalighi, A. H., Drach, A., Bloodworth, C. H., Pierce, E. L., Yoganathan, A. P., Gorman, R. C., Gorman, J. H. & Sacks, M. S., Feb 1 2017, In : Annals of Biomedical Engineering. 45, 2, p. 378-393 16 p.

Research output: Contribution to journalArticle

Geometry
Muscle
Repair
Bearings (structural)
Binary trees
9 Citations (Scopus)
Tissue
Geometry
Collagen
Glutaral
Fibers
6 Citations (Scopus)

On the Functional Role of Valve Interstitial Cell Stress Fibers: A Continuum Modeling Approach

Sakamoto, Y., Buchanan, R. M., Sanchez-Adams, J., Guilak, F. & Sacks, M. S., Feb 1 2017, In : Journal of Biomechanical Engineering. 139, 2, 021002.

Research output: Contribution to journalArticle

Stress Fibers
Fibers
Strain rate
Actins
Chemical activation
8 Citations (Scopus)

On the in vivo function of the mitral heart valve leaflet: insights into tissue–interstitial cell biomechanical coupling

Lee, C. H., Zhang, W., Feaver, K., Gorman, R. C., Gorman, J. H. & Sacks, M. S., Oct 1 2017, In : Biomechanics and Modeling in Mechanobiology. 16, 5, p. 1613-1632 20 p.

Research output: Contribution to journalArticle

Heart Valves
Mitral Valve
Tissue
Cell
Kinematics

On the 'slip-on' buckle arrestor for offshore pipelines.

Kyriakides, S. & Babcock, C. D., Jan 1 2017, In : TRANS. ASME J. PRESSURE VESSEL TECHNOL.. 102, 2 , May 1980, p. 188-193 6 p.

Research output: Contribution to journalArticle

Offshore pipelines
Pipelines
Pipe

OPTIMAL RUNGE-KUTTA METHODS.

Hull, D. G. & Bettis, D. G., Jan 1 2017, In : Am Astron Soc/AIAA Astrodyn Spec Conf.

Research output: Contribution to journalArticle

Runge Kutta methods
Function evaluation
10 Citations (Scopus)

Regulation of valve interstitial cell homeostasis by mechanical deformation: Implications for heart valve disease and surgical repair

Ayoub, S., Lee, C. H., Driesbaugh, K. H., Anselmo, W., Hughes, C. T., Ferrari, G., Gorman, R. C., Gorman, J. H. & Sacks, M. S., Oct 1 2017, In : Journal of the Royal Society Interface. 14, 135, 20170580.

Research output: Contribution to journalArticle

Open Access
Heart Valve Diseases
Homeostasis
Repair
Tissue
Mitral Valve

SENSITIVITY ANALYSIS OF SHORT-ARC STATION COORDINATE DETERMINATIONS FROM RANGE DATA.

Schutz, B. E. & Tapley, B. D., Jan 1 2017, In : Am Astron Soc/AIAA Astrodyn Spec Conf.

Research output: Contribution to journalArticle

Sensitivity analysis
Satellites
Drag
Earth (planet)
Geometry

THREE-DIMENSIONAL G-CONSTRAINED SHUTTLE BOOST TRAJECTORY OPTIMIZATION USING A MIN-H/SECANT HYBRID ALGORITHM.

Gottlieb, R. G. & Fowler, W. T., Jan 1 2017, In : Am Astron Soc/AIAA Astrodyn Spec Conf.

Research output: Contribution to journalArticle

Trajectories
2016
6 Citations (Scopus)

A Comparison of Artificial Viscosity, Limiters, and Filters, for High Order Discontinuous Galerkin Solutions in Nonlinear Settings

Michoski, C., Dawson, C. N., Kubatko, E. J., Wirasaet, D., Brus, S. & Westerink, J. J., Jan 1 2016, In : Journal of Scientific Computing. 66, 1, p. 406-434 29 p.

Research output: Contribution to journalArticle

Artificial Viscosity
Nonlinear Systems of Equations
Limiter
Discontinuous Galerkin
Limiters
5 Citations (Scopus)

A fuzzy-stochastic multiscale model for fiber composites: A one-dimensional study

Babuška, I. & Motamed, M., Apr 15 2016, In : Computer Methods in Applied Mechanics and Engineering. 302, p. 109-130 22 p.

Research output: Contribution to journalArticle

multiscale models
fiber composites
Stochastic models
Fibers
Composite materials
495 Citations (Scopus)

A graphene-based electrochemical device with thermoresponsive microneedles for diabetes monitoring and therapy

Lee, H., Choi, T. K., Lee, Y. B., Cho, H. R., Ghaffari, R., Wang, L., Choi, H. J., Chung, T. D., Lu, N., Hyeon, T., Choi, S. H. & Kim, D. H., Jun 1 2016, In : Nature Nanotechnology. 11, 6, p. 566-572 7 p.

Research output: Contribution to journalArticle

Graphite
Medical problems
Graphene
therapy
graphene
9 Citations (Scopus)

A Hybridized Discontinuous Galerkin Method for the Nonlinear Korteweg–de Vries Equation

Samii, A., Panda, N., Michoski, C. & Dawson, C., Jul 1 2016, In : Journal of Scientific Computing. 68, 1, p. 191-212 22 p.

Research output: Contribution to journalArticle

Discontinuous Galerkin Method
Galerkin methods
Korteweg-de Vries Equation
Nonlinear Equations
Trace
26 Citations (Scopus)

A meso-scale layer-specific structural constitutive model of the mitral heart valve leaflets

Zhang, W., Ayoub, S., Liao, J. & Sacks, M. S., Mar 1 2016, In : Acta Biomaterialia. 32, p. 238-255 18 p.

Research output: Contribution to journalArticle

Structural Models
Heart Valves
Constitutive models
Mitral Valve
Collagen
8 Citations (Scopus)

An inverse modeling approach for semilunar heart valve leaflet mechanics: exploitation of tissue structure

Aggarwal, A. & Sacks, M. S., Aug 1 2016, In : Biomechanics and Modeling in Mechanobiology. 15, 4, p. 909-932 24 p.

Research output: Contribution to journalArticle

Inverse Modeling
Heart Valves
Mechanics
Exploitation
Tissue
18 Citations (Scopus)

A novel fibre-ensemble level constitutive model for exogenous cross-linked collagenous tissues

Sacks, M. S., Zhang, W. & Wognum, S., Feb 6 2016, In : Interface Focus. 6, 1, 20150090.

Research output: Contribution to journalArticle

Constitutive models
Tissue
Collagen
Fibers
Structural Models
8 Citations (Scopus)

A parallel and adaptive hybridized discontinuous Galerkin method for anisotropic nonhomogeneous diffusion

Samii, A., Michoski, C. & Dawson, C. N., Jun 1 2016, In : Computer Methods in Applied Mechanics and Engineering. 304, p. 118-139 22 p.

Research output: Contribution to journalArticle

Galerkin method
Galerkin methods
Fluxes
scalars
grids
4 Citations (Scopus)

A study on simultaneous design of a Hall Effect Thruster and its low-thrust trajectory

Kwon, K., Lantoine, G., Russell, R. P. & Mavris, D. N., Feb 1 2016, In : Acta Astronautica. 119, p. 34-47 14 p.

Research output: Contribution to journalArticle

Hall effect
Trajectories
Radiation belts
Hall thrusters
Orbital transfer
6 Citations (Scopus)

Avoiding the local-minimum problem in multi-agent systems with limited sensing and communication

Okamoto, M. & Akella, M. R., Jun 10 2016, In : International Journal of Systems Science. 47, 8, p. 1943-1952 10 p.

Research output: Contribution to journalArticle

Multi agent systems
Local Minima
Multi-agent Systems
Sensing
Communication
15 Citations (Scopus)

Bayesian inference and model comparison for metallic fatigue data

Babuška, I., Sawlan, Z., Scavino, M., Szabó, B. & Tempone, R., Jun 1 2016, In : Computer Methods in Applied Mechanics and Engineering. 304, p. 171-196 26 p.

Research output: Contribution to journalArticle

inference
Fatigue of materials
quantiles
ranking
fatigue life