Carla Vandenberg, PharmD

Livestrong Cancer Institute; Developmental Therapeutics Lab Co-Director; Associate Professor

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Carla VanDenBerg's research interests include receptor tyrosine kinases (RTKs) convey pro-tumorigenic responses in breast, colon, lung and prostate cancer. Her lab focuses on a group of proteins known as JNK (c-Jun N-terminal Kinases) which are activated by receptor tyrosine kinases in breast cancer models. Ultimately, VanDenBerg and her team hope to evaluate if JNK can be therapeutically targeted to treat breast cancer patients.

Fingerprint Dive into the research topics where Carla Vandenberg is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Breast Neoplasms Medicine & Life Sciences
JNK Mitogen-Activated Protein Kinases Medicine & Life Sciences
Insulin-Like Growth Factor I Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Cells Chemical Compounds
Nude Mice Medicine & Life Sciences
Tumors Chemical Compounds
Cell Movement Medicine & Life Sciences

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Research Output 1994 2019

1 Citation (Scopus)

Single-cell RNA sequencing of lung adenocarcinoma reveals heterogeneity of immune response-related genes

Ma, K. Y., Schonnesen, A. A., Brock, A., Van Den Berg, C., Eckhardt, S. G., Liu, Z. & Jiang, N., Feb 21 2019, In : JCI Insight. 4, 4

Research output: Contribution to journalArticle

Open Access
RNA Sequence Analysis
Tumor Escape
Cell Line
5 Citations (Scopus)

"A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib"

Ebelt, N. D., Kaoud, T. S., Edupuganti, R., Van Ravenstein, S., Dalby, K. N. & Van Den Berg, C. L., Jan 1 2017, In : Oncotarget. 8, 62, p. 104894-104912 19 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
JNK Mitogen-Activated Protein Kinases
GATA1 Transcription Factor
Breast Neoplasms
8 Citations (Scopus)

Extracellular Matrix Stiffening Induces a Malignant Phenotypic Transition in Breast Epithelial Cells

Stowers, R. S., Allen, S. C., Sanchez, K., Davis, C. L., Ebelt, N. D., Van Den Berg, C. & Suggs, L. J., Feb 1 2017, In : Cellular and Molecular Bioengineering. 10, 1, p. 114-123 10 p.

Research output: Contribution to journalArticle

Extracellular Matrix
Epithelial Cells
2 Citations (Scopus)

Serotonin Analogues as Inhibitors of Breast Cancer Cell Growth

Jose, J., Tavares, C. D. J., Ebelt, N. D., Lodi, A., Edupuganti, R., Xie, X., Devkota, A. K., Kaoud, T. S., Vandenberg, C., Anslyn, E. V., Tiziani, S., Bartholomeusz, C. & Dalby, K., Oct 12 2017, In : ACS Medicinal Chemistry Letters. 8, 10, p. 1072-1076 5 p.

Research output: Contribution to journalArticle

Cell growth
Breast Neoplasms
28 Citations (Scopus)

ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion

Chen, W. T., Ebelt, N. D., Stracker, T. H., Xhemalce, B., Van Den Berg, C. L. & Miller, K. M., Jun 1 2015, In : eLife. 4, JUNE, e07270.

Research output: Contribution to journalArticle

Ataxia Telangiectasia
Oxidative stress
Cell Movement
Oxidative Stress