Carla Vandenberg, PharmD

Livestrong Cancer Institute; Developmental Therapeutics Lab Co-Director; Associate Professor

19942019
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Personal profile

Bio

Carla VanDenBerg's research interests include receptor tyrosine kinases (RTKs) convey pro-tumorigenic responses in breast, colon, lung and prostate cancer. Her lab focuses on a group of proteins known as JNK (c-Jun N-terminal Kinases) which are activated by receptor tyrosine kinases in breast cancer models. Ultimately, VanDenBerg and her team hope to evaluate if JNK can be therapeutically targeted to treat breast cancer patients.

Fingerprint Dive into the research topics where Carla Vandenberg is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Breast Neoplasms Medicine & Life Sciences
JNK Mitogen-Activated Protein Kinases Medicine & Life Sciences
Insulin-Like Growth Factor I Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Cells Chemical Compounds
Nude Mice Medicine & Life Sciences
Tumors Chemical Compounds
Cell Movement Medicine & Life Sciences

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Research Output 1994 2019

Single-cell RNA sequencing of lung adenocarcinoma reveals heterogeneity of immune response-related genes

Ma, K. Y., Schonnesen, A. A., Brock, A., Vandenberg, C., Eckhardt, S. G., Liu, Z. & Jiang, N., Feb 21 2019, In : JCI insight. 4, 4

Research output: Contribution to journalArticle

Open Access
RNA Sequence Analysis
Immunotherapy
Genes
Tumor Escape
Cell Line
3 Citations (Scopus)

"A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib"

Ebelt, N. D., Kaoud, T. S., Edupuganti, R., Van Ravenstein, S., Dalby, K. N. & Vandenberg, C., Jan 1 2017, In : Oncotarget. 8, 62, p. 104894-104912 19 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
JNK Mitogen-Activated Protein Kinases
GATA1 Transcription Factor
Antioxidants
Breast Neoplasms
8 Citations (Scopus)

Extracellular Matrix Stiffening Induces a Malignant Phenotypic Transition in Breast Epithelial Cells

Stowers, R. S., Allen, S. C., Sanchez, K., Davis, C. L., Ebelt, N. D., Vandenberg, C. & Suggs, L. J., Feb 1 2017, In : Cellular and Molecular Bioengineering. 10, 1, p. 114-123 10 p.

Research output: Contribution to journalArticle

Extracellular Matrix
Tumors
Tumor
Breast
Epithelial Cells
2 Citations (Scopus)

Serotonin Analogues as Inhibitors of Breast Cancer Cell Growth

Jose, J., Tavares, C. D. J., Ebelt, N. D., Lodi, A., Edupuganti, R., Xie, X., Devkota, A. K., Kaoud, T. S., Vandenberg, C., Anslyn, E. V., Tiziani, S., Bartholomeusz, C. & Dalby, K. N., Oct 12 2017, In : ACS Medicinal Chemistry Letters. 8, 10, p. 1072-1076 5 p.

Research output: Contribution to journalArticle

Cell growth
Serotonin
Cells
Breast Neoplasms
Growth
25 Citations (Scopus)

ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion

Chen, W. T., Ebelt, N. D., Stracker, T. H., Xhemalce, B., Vandenberg, C. & Miller, K. M., Jun 1 2015, In : eLife. 4, JUNE, e07270.

Research output: Contribution to journalArticle

Ataxia Telangiectasia
Oxidative stress
Interleukin-8
Cell Movement
Oxidative Stress