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Research Output 2002 2019

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Article
2019

Aberrant DNA polymerase beta enhances H. Pylori infection induced genomic instability and gastric carcinogenesis in mice

Zhao, S., Thakur, M., Klattenhoff, A. W. & Kidane, D., Jun 2019, In : Cancers. 11, 6, 843.

Research output: Contribution to journalArticle

Open Access
DNA Polymerase beta
Genomic Instability
Pylorus
Stomach
Carcinogenesis

Mutation in dna polymerase beta causes spontaneous chromosomal instability and inflammation-associated carcinogenesis in mice

Zhao, S., Klattenho, A. W., Thakur, M., Sebastian, M. & Kidane, D., Aug 2019, In : Cancers. 11, 8, 1160.

Research output: Contribution to journalArticle

Open Access
Chromosomal Instability
Carcinogenesis
Inflammation
Mutation
Neoplasms
2017

Dynamics of Base Excision Repair at the Maternal-Fetal Interface in Pregnancies Complicated by Preeclampsia

Tadesse, S., Norwitz, N. G., Guller, S., Arcuri, F., Toti, P., Norwitz, E. R. & Kidane, D., Jan 1 2017, In : Reproductive Sciences. 24, 6, p. 856-864 9 p.

Research output: Contribution to journalArticle

Pre-Eclampsia
DNA Repair
Endonucleases
Oxidative Stress
Mothers
4 Citations (Scopus)

Loss of NEIL3 DNA glycosylase markedly increases replication associated double strand breaks and enhances sensitivity to ATR inhibitor in glioblastoma cells

Klattenhoff, A. W., Thakur, M., Chu, C. S., Ray, D., Habib, S. L. & Kidane, D., Jan 1 2017, In : Oncotarget. 8, 68, p. 112942-112958 17 p.

Research output: Contribution to journalArticle

DNA Glycosylases
Glioblastoma
DNA Damage
DNA
Replication Protein A
2016
21 Citations (Scopus)

Novel protective mechanism of reducing renal cell damage in diabetes: Activation AMPK by AICAR increased NRF2/OGG1 proteins and reduced oxidative DNA damage

Habib, S. L., Yadav, A., Kidane, D., Weiss, R. H. & Liang, S., Nov 16 2016, In : Cell Cycle. 15, 22, p. 3048-3059 12 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
DNA Damage
Raptors
Kidney
Glucose
2015
3 Citations (Scopus)

Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaks

Rozacky, J., Nemec, A. A., Sweasy, J. B. & Kidane, D., Jan 1 2015, In : Oncotarget. 6, 27, p. 24474-24487 14 p.

Research output: Contribution to journalArticle

DNA Polymerase beta
DNA Replication
Stomach Neoplasms
DNA-Directed DNA Polymerase
DNA Repair
2014
29 Citations (Scopus)

Accumulation of abasic sites induces genomic instability in normal human gastric epithelial cells during Helicobacter pylori infection

Kidane, D., Murphy, D. L. & Sweasy, J. B., Jan 1 2014, In : Oncogenesis. 3, 11, e128.

Research output: Contribution to journalArticle

Genomic Instability
Helicobacter Infections
Helicobacter pylori
DNA Damage
Stomach
14 Citations (Scopus)

In vivo and in vitro evidence for placental DNA damage in preeclampsia

Tadesse, S., Kidane, D., Guller, S., Luo, T., Norwitz, N. G., Arcuri, F., Toti, P. & Norwitz, E. R., Jan 22 2014, In : PloS one. 9, 1, e86791.

Research output: Contribution to journalArticle

pre-eclampsia
Pre-Eclampsia
DNA damage
DNA Damage
placenta
20 Citations (Scopus)

Mutation of POLB causes lupus in mice

Senejani, A. G., Liu, Y., Kidane, D., Maher, S. E., Zeiss, C. J., Park, H. J., Kashgarian, M., McNiff, J. M., Zelterman, D., Bothwell, A. L. M. & Sweasy, J. B., Jan 3 2014, In : Cell Reports. 6, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Genes
Immunoglobulin Heavy Chains
Mutation
Pathology
2013
22 Citations (Scopus)

Germ-line variant of human NTH1 DNA glycosylase induces genomic instability and cellular transformation

Galick, H. A., Kathe, S., Liu, M., Robey-Bond, S., Kidane, D., Wallace, S. S. & Sweasy, J. B., Aug 27 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 35, p. 14314-14319 6 p.

Research output: Contribution to journalArticle

DNA Glycosylases
Genomic Instability
Germ Cells
DNA Repair
Pyrimidines
6 Citations (Scopus)

Kinesin 5B (KIF5B) Is Required for Progression through Female Meiosis and Proper Chromosomal Segregation in Mitotic Cells

Kidane, D., Sakkas, D., Nottoli, T., McGrath, J. & Sweasy, J. B., Apr 1 2013, In : PloS one. 8, 4, e58585.

Research output: Contribution to journalArticle

Kinesin
kinesin
Meiosis
meiosis
Cell Division
2012
2 Citations (Scopus)

Tipping the balance in the powerhouse of the cell to "protect" colorectal cancer

Kidane, D. & Sweasy, J. B., Jun 1 2012, In : PLoS Genetics. 8, 6, e1002758.

Research output: Contribution to journalArticle

mitochondrion
DNA repair
colorectal neoplasms
Mitochondrial DNA
DNA Repair
2011
11 Citations (Scopus)

DNA polymerase beta is critical for genomic stability of sperm cells

Kidane, D., Dalal, S., Keh, A., Liu, Y., Zelterman, D. & Sweasy, J. B., Apr 3 2011, In : DNA Repair. 10, 4, p. 390-397 8 p.

Research output: Contribution to journalArticle

DNA Polymerase beta
Genomic Instability
Spermatozoa
Genes
pol Genes
2010
36 Citations (Scopus)

DNA polymerase Β is critical for mouse meiotic synapsis

Kidane, D., Jonason, A. S., Gorton, T. S., Mihaylov, I., Pan, J., Keeney, S., De Rooij, D. G., Ashley, T., Keh, A., Liu, Y., Banerjee, U., Zelterman, D. & Sweasy, J. B., Jan 1 2010, In : EMBO Journal. 29, 2, p. 410-423 14 p.

Research output: Contribution to journalArticle

Meiotic Prophase I
Chromosome Pairing
DNA-Directed DNA Polymerase
Chromosomes
Spermatocytes
2009
40 Citations (Scopus)

Evidence for different pathways during horizontal gene transfer in competent Bacillus subtilis cells

Kidane, D., Carrasco, B., Manfredi, C., Rothmaier, K., Ayora, S., Tadesse, S., Alonso, J. C. & Graumann, P. L., Sep 2009, In : PLoS Genetics. 5, 9, e1000630.

Research output: Contribution to journalArticle

Horizontal Gene Transfer
gene transfer
Bacillus subtilis
DNA
plasmids
2006
39 Citations (Scopus)

Bacillus subtilis SbcC protein plays an important role in DNA inter-strand cross-link repair

Mascarenhas, J., Sanchez, H., Tadesse, S., Kidane, D., Krisnamurthy, M., Alonzo, J. C. & Graumann, P. L., Jun 16 2006, In : BMC Molecular Biology. 7, 20.

Research output: Contribution to journalArticle

Bacilli
Bacillus subtilis
DNA Repair
Mitomycin
Repair
15 Citations (Scopus)

Leishmania aethiopica: Strain identification and characterization of superoxide dismutase-B genes

Genetu, A., Gadisa, E., Aseffa, A., Barr, S., Lakew, M., Jirata, D., Kuru, T., Kidane-Mulat, D., Hunegnaw, M. & Gedamu, L., Aug 1 2006, In : Experimental Parasitology. 113, 4, p. 221-226 6 p.

Research output: Contribution to journalArticle

Leishmania
Superoxide Dismutase
Genes
Specimen Handling
Cutaneous Leishmaniasis
60 Citations (Scopus)

Recruitment of Bacillus subtilis RecN to DNA double-strand breaks in the absence of DNA end processing

Sanchez, H., Kidane, D., Cozar, M. C., Graumann, P. L. & Alonso, J. C., Jan 1 2006, In : Journal of bacteriology. 188, 2, p. 353-360 8 p.

Research output: Contribution to journalArticle

Double-Stranded DNA Breaks
Bacillus subtilis
DNA
Single-Stranded DNA
RecQ Helicases
2005
66 Citations (Scopus)

Dynamic formation of RecA filaments at DNA double strand break repair centers in live cells

Kidane, D. & Graumann, P. L., Sep 1 2005, In : Journal of Cell Biology. 170, 3, p. 357-366 10 p.

Research output: Contribution to journalArticle

Double-Stranded DNA Breaks
Rec A Recombinases
DNA Polymerase I
Bacillus subtilis
Microscopy
75 Citations (Scopus)

Intracellular protein and DNA dynamics in competent Bacillus subtilis cells

Kidane-Mulat, D. & Graumann, P. L., Jul 15 2005, In : Cell. 122, 1, p. 73-84 12 p.

Research output: Contribution to journalArticle

Bacilli
Bacillus subtilis
Mental Competency
Machinery
Poles
50 Citations (Scopus)

The RuvAB branch migration translocase and RecU Holliday junction resolvase are required for double-stranded DNA break repair in Bacillus subtilis

Sanchez, H., Kidane, D., Reed, P., Curtis, F. A., Cozar, M. C., Graumann, P. L., Sharples, G. J. & Alonso, J. C., Nov 1 2005, In : Genetics. 171, 3, p. 873-883 11 p.

Research output: Contribution to journalArticle

Holliday Junction Resolvases
Double-Stranded DNA Breaks
Bacillus subtilis
DNA Repair
Escherichia coli
2004
3 Citations (Scopus)

Female genital tuberculosis in Ethiopia

Abebe, M., Lakew, M., Kidane-Mulat, D., Lakew, Z., Kiros, K. & Harboe, M., Dec 1 2004, In : Ethiopian Medical Journal. 42, SUPPL. 1, p. 37-41 5 p.

Research output: Contribution to journalArticle

Female Genital Tuberculosis
Ethiopia
Polymerase Chain Reaction
CD4-CD8 Ratio
Curettage
28 Citations (Scopus)

Female genital tuberculosis in Ethiopia

Abebe, M., Lakew, M., Kidane, D., Lakew, Z., Kiros, K. & Harboe, M., Mar 2004, In : International Journal of Gynecology and Obstetrics. 84, 3, p. 241-246 6 p.

Research output: Contribution to journalArticle

Female Genital Tuberculosis
Ethiopia
Polymerase Chain Reaction
CD4-CD8 Ratio
Curettage
2 Citations (Scopus)

T cell mediated immune responses in patients with tuberculous lymphadenitis from Butajira, Southern Ethiopia

Habte, A., Geletu, M., Olobo, J. O., Kidane-Mulat, D., Negesse, Y., Yassin, M. A., Kifle, B., Abate, G., Harboe, M. & Aseffa, A., Dec 1 2004, In : Ethiopian Medical Journal. 42, SUPPL. 1, p. 29-35 7 p.

Research output: Contribution to journalArticle

Lymph Node Tuberculosis
Ethiopia
Tuberculosis
T-Lymphocytes
Blood Cells
96 Citations (Scopus)
Double-Stranded DNA Breaks
Bacillus subtilis
Bacteria
Chromosome Pairing
Proteins
2003
28 Citations (Scopus)

Diagnosis of tuberculous lymphadenitis in Butajira, rural Ethiopia

Yassin, M. A., Olobo, J. O., Kidane, D., Negesse, Y., Shimeles, E., Tadesse, A., Demissie, A., Britton, S., Harboe, M., Aseffa, A. & Abate, G., Jul 16 2003, In : Scandinavian Journal of Infectious Diseases. 35, 4, p. 240-243 4 p.

Research output: Contribution to journalArticle

Lymph Node Tuberculosis
Ethiopia
Lymphadenitis
Cell Biology
Virus Diseases
35 Citations (Scopus)

Nasal carriage of Mycobacterium leprae DNA in healthy individuals in Lega Robi village, Ethiopia

Beyene, D., Aseffa, A., Harboe, M., Kidane, D., MacDonald, M., Klatser, P. R., Bjune, G. A. & Smith, W. C. S., Oct 1 2003, In : Epidemiology and Infection. 131, 2, p. 841-848 8 p.

Research output: Contribution to journalArticle

Mycobacterium leprae
Ethiopia
Nose
DNA
Leprosy
2002
79 Citations (Scopus)

Identification of the causative organism of tuberculous lymphadenitis in Ethiopia by PCR

Kidane, D., Olobo, J. O., Habte, A., Negesse, Y., Aseffa, A., Abate, G., Yassin, M. A., Bereda, K. & Harboe, M., Nov 1 2002, In : Journal of Clinical Microbiology. 40, 11, p. 4230-4234 5 p.

Research output: Contribution to journalArticle

Lymph Node Tuberculosis
Ethiopia
Mycobacterium tuberculosis
Polymerase Chain Reaction
Needles