Everett Stone, PhD

Assistant Professor

20052019
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Fingerprint Dive into the research topics where Everett Stone is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Arginase Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Arginine Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Citrulline Medicine & Life Sciences
Tumors Chemical Compounds
Argininosuccinate Synthase Medicine & Life Sciences

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Research Output 2005 2019

9 Citations (Scopus)

A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity

Cao, J. Y., Poddar, A., Magtanong, L., Lumb, J. H., Mileur, T. R., Reid, M. A., Dovey, C. M., Wang, J., Locasale, J. W., Stone, E., Cole, S. P. C., Carette, J. E. & Dixon, S. J., Feb 5 2019, In : Cell Reports. 26, 6, p. 1544-1556.e8

Research output: Contribution to journalArticle

Open Access
Haploidy
Glutathione
Genes
Genome
Mutagenesis
25 Citations (Scopus)

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

Wang, W., Green, M., Choi, J. E., Gijón, M., Kennedy, P. D., Johnson, J. K., Liao, P., Lang, X., Kryczek, I., Sell, A., Xia, H., Zhou, J., Li, G., Li, J., Li, W., Wei, S., Vatan, L., Zhang, H., Szeliga, W., Gu, W. & 10 others, Liu, R., Lawrence, T. S., Lamb, C., Tanno, Y., Cieslik, M., Stone, E., Georgiou, G., Chan, T. A., Chinnaiyan, A. & Zou, W., May 9 2019, In : NATURE. 569, 7755, p. 270-274 5 p.

Research output: Contribution to journalLetter

Immunotherapy
T-Lymphocytes
Neoplasms
Cystine
Interferon-gamma

Optimization of a nicotine degrading enzyme for potential use in treatment of nicotine addiction

Thisted, T., Biesova, Z., Walmacq, C., Stone, E., Rodnick-Smith, M., Ahmed, S. S., Horrigan, S. K., Van Engelen, B., Reed, C. & Kalnik, M. W., Aug 2 2019, In : BMC Biotechnology. 19, 1, 56.

Research output: Contribution to journalArticle

Open Access
Nicotine
Enzymes
Therapeutics
Therapeutic Uses
Half-Life
19 Citations (Scopus)

Reversal of indoleamine 2,3-dioxygenase–Mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme

Triplett, T. A., Garrison, K. C., Marshall, N., Donkor, M., Blazeck, J., Lamb, C., Qerqez, A., Dekker, J. D., Tanno, Y., Lu, W. C., Karamitros, C. S., Ford, K., Tan, B., Zhang, X. M., McGovern, K., Coma, S., Kumada, Y., Yamany, M. S., Sentandreu, E., Fromm, G. & 6 others, Tiziani, S., Schreiber, T. H., Manfredi, M., Ehrlich, L. I. R., Stone, E. & Georgiou, G., Sep 1 2018, In : Nature Biotechnology. 36, 8

Research output: Contribution to journalLetter

Tryptophan Oxygenase
Kynurenine
Tumor Microenvironment
Tumors
Enzymes
18 Citations (Scopus)

Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine

Poursaitidis, I., Wang, X., Crighton, T., Labuschagne, C., Mason, D., Cramer, S. L., Triplett, K., Roy, R., Pardo, O. E., Seckl, M. J., Rowlinson, S. W., Stone, E. & Lamb, R. F., Mar 14 2017, In : Cell Reports. 18, 11, p. 2547-2556 10 p.

Research output: Contribution to journalArticle

Open Access
Cystine
Cell death
Oncogenes
Epidermal Growth Factor Receptor
Nutrients