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George Georgiou, PhD

Professor; Professor (Medical)

1985 …2019
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Fingerprint Dive into the research topics where George Georgiou is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Escherichia coli Medicine & Life Sciences
Antibodies Medicine & Life Sciences
Proteins Medicine & Life Sciences
Libraries Medicine & Life Sciences
Periplasm Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Single-Chain Antibodies Medicine & Life Sciences
Disulfides Medicine & Life Sciences

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Research Output 1985 2019

3 Citations (Scopus)

An engineered human fc variant with exquisite selectivity for FcγRIIIaV158 reveals that ligation of FcγRIIIa mediates potent antibody dependent cellular phagocytosis with GM-CSF-differentiated macrophages

Kang, T. H., Lee, C. H., Delidakis, G., Jung, J., Goff, O. R. L., Lee, J., Kim, J. E., Charab, W., Bruhns, P. & Georgiou, G., Jan 1 2019, In : Frontiers in immunology. 10, MAR, 562.

Research output: Contribution to journal › Article

Open Access
IgG Receptors
Granulocyte-Macrophage Colony-Stimulating Factor
Phagocytosis
Ligation
Antibody-Dependent Cell Cytotoxicity
25 Citations (Scopus)

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

Wang, W., Green, M., Choi, J. E., Gijón, M., Kennedy, P. D., Johnson, J. K., Liao, P., Lang, X., Kryczek, I., Sell, A., Xia, H., Zhou, J., Li, G., Li, J., Li, W., Wei, S., Vatan, L., Zhang, H., Szeliga, W., Gu, W. & 10 others, Liu, R., Lawrence, T. S., Lamb, C., Tanno, Y., Cieslik, M., Stone, E., Georgiou, G., Chan, T. A., Chinnaiyan, A. & Zou, W., May 9 2019, In : NATURE. 569, 7755, p. 270-274 5 p.

Research output: Contribution to journal › Letter

Immunotherapy
T-Lymphocytes
Neoplasms
Cystine
Interferon-gamma
8 Citations (Scopus)

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual

Krebs, S. J., Kwon, Y. D., Schramm, C. A., Law, W. H., Donofrio, G., Zhou, K. H., Gift, S., Dussupt, V., Georgiev, I. S., Schätzle, S., McDaniel, J. R., Lai, Y. T., Sastry, M., Zhang, B., Jarosinski, M. C., Ransier, A., Chenine, A. L., Asokan, M., Bailer, R. T., Bose, M. & 41 others, Cagigi, A., Cale, E. M., Chuang, G. Y., Darko, S., Driscoll, J. I., Druz, A., Gorman, J., Laboune, F., Louder, M. K., McKee, K., Mendez, L., Moody, M. A., O'Sullivan, A. M., Owen, C., Peng, D., Rawi, R., Sanders-Buell, E., Shen, C. H., Shiakolas, A. R., Stephens, T., Tsybovsky, Y., Tucker, C., Verardi, R., Wang, K., Zhou, J., Zhou, T., Georgiou, G., Alam, S. M., Haynes, B. F., Rolland, M., Matyas, G. R., Polonis, V. R., McDermott, A. B., Douek, D. C., Shapiro, L., Tovanabutra, S., Michael, N. L., Mascola, J. R., Robb, M. L., Kwong, P. D. & Doria-Rose, N. A., Mar 19 2019, In : Immunity. 50, 3, p. 677-691.e13

Research output: Contribution to journal › Article

HIV Antibodies
Germ-Line Mutation
Neutralizing Antibodies
HIV-1
Vaccines
9 Citations (Scopus)

Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations

Lee, J., Paparoditis, P., Horton, A. P., Frühwirth, A., McDaniel, J. R., Jung, J., Boutz, D. R., Hussein, D. A., Tanno, Y., Pappas, L., Ippolito, G. C., Corti, D., Lanzavecchia, A. & Georgiou, G., Mar 13 2019, In : Cell Host and Microbe. 25, 3, p. 367-376.e5

Research output: Contribution to journal › Article

Hemagglutinins
Human Influenza
Vaccination
Antibodies
Serum

Rapid Screen for Tyrosine Kinase Inhibitor Resistance Mutations and Substrate Specificity

Taft, J. M., Georgeon, S., Allen, C., Reckel, S., Desautelle, J., Hantschel, O., Georgiou, G. & Iverson, B. L., Sep 20 2019, In : ACS chemical biology. 14, 9, p. 1888-1895 8 p.

Research output: Contribution to journal › Article

Substrate Specificity
Protein-Tyrosine Kinases
Phosphotransferases
Mutation
Substrates