Hyun Jung Kim, PhD

Assistant Professor

19992020
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Research Output 1999 2020

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Article
2020
1 Citation (Scopus)

New approaches towards the discovery and evaluation of bioactive peptides from natural resources

Kang, N. J., Jin, H. S., Lee, S. E., Kim, H. J., Koh, H. & Lee, D. W., Jan 2 2020, In : Critical Reviews in Environmental Science and Technology. 50, 1, p. 72-103 32 p.

Research output: Contribution to journalArticle

Natural resources
peptide
Peptides
natural resource
Proteins
2019
3 Citations (Scopus)

A robust longitudinal co-culture of obligate anaerobic gut microbiome with human intestinal epithelium in an anoxic-oxic interface-on-a-chip

Shin, W., Wu, A., Massidda, M. W., Foster, C., Thomas, N., Lee, D. W., Koh, H., Ju, Y., Kim, J. & Kim, H. J., Jan 1 2019, In : Frontiers in Bioengineering and Biotechnology. 7, FEB, 13.

Research output: Contribution to journalArticle

Open Access
Intestinal Mucosa
Coculture Techniques
Crosstalk
Anaerobic Bacteria
Epithelial Cells

Human Intestinal Morphogenesis Controlled by Transepithelial Morphogen Gradient and Flow-Dependent Physical Cues in a Microengineered Gut-on-a-Chip

Shin, W., Hinojosa, C. D., Ingber, D. E. & Kim, H. J., May 31 2019, In : iScience. 15, p. 391-406 16 p.

Research output: Contribution to journalArticle

Open Access
Developmental Biology
Tissue Engineering
Morphogenesis
Cues
Cell Biology
2018
2 Citations (Scopus)

Development and evaluation of a CEACAM6-targeting theranostic nanomedicine for photoacoustic-based diagnosis and chemotherapy of metastatic cancer

Lee, H., Jang, Y., Park, S., Jang, H., Park, E. J., Kim, H. J. & Kim, H., Jan 1 2018, In : Theranostics. 8, 15, p. 4247-4261 15 p.

Research output: Contribution to journalArticle

Open Access
Carcinoembryonic Antigen
Cell Adhesion Molecules
Anoikis
Drug Therapy
Neoplasms
17 Citations (Scopus)
Open Access
Microbiota
Dextran Sulfate
Inflammation
Oxidative Stress
Probiotics
20 Citations (Scopus)

Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip article

Jalili-Firoozinezhad, S., Prantil-Baun, R., Jiang, A., Potla, R., Mammoto, T., Weaver, J. C., Ferrante, T. C., Kim, H. J., Cabral, J. M. S., Levy, O. & Ingber, D. E., Feb 1 2018, In : Cell Death and Disease. 9, 2, 223.

Research output: Contribution to journalArticle

Open Access
Radiation Injuries
Cell Death
Radiation
Pharmaceutical Preparations
Lab-On-A-Chip Devices
2017
15 Citations (Scopus)

Emulating Host-Microbiome Ecosystem of Human Gastrointestinal Tract in Vitro

Park, G. S., Park, M. H., Shin, W., Zhao, C., Sheikh, S., Oh, S. J. & Kim, H. J., Jun 1 2017, In : Stem Cell Reviews and Reports. 13, 3, p. 321-334 14 p.

Research output: Contribution to journalArticle

Microbiota
Ecosystem
Gastrointestinal Tract
Organoids
Drug and Narcotic Control
2016
16 Citations (Scopus)

Co-culture of living microbiome with microengineered human intestinal villi in a gut-on-a-chip microfluidic device

Kim, H. J., Lee, J., Choi, J. H., Bahinski, A. & Ingber, D. E., Aug 30 2016, In : Journal of Visualized Experiments. 2016, 114, e54344.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Microbiota
Coculture Techniques
Microfluidics
Ecosystems
225 Citations (Scopus)
Open Access
Microbiota
Inflammation
Peristalsis
Epithelial Cells
Ileus
2015
210 Citations (Scopus)

Engineered in vitro disease models

Benam, K. H., Dauth, S., Hassell, B., Herland, A., Jain, A., Jang, K. J., Karalis, K., Kim, H. J., MacQueen, L., Mahmoodian, R., Musah, S., Torisawa, Y. S., Van Der Meer, A. D., Villenave, R., Yadid, M., Parker, K. K. & Ingber, D. E., Jan 1 2015, In : Annual Review of Pathology: Mechanisms of Disease. 10, p. 195-262 68 p.

Research output: Contribution to journalArticle

Blood Vessels
Microtechnology
Animal Disease Models
Musculoskeletal System
Pluripotent Stem Cells
50 Citations (Scopus)

Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems

Odijk, M., Van Der Meer, A. D., Levner, D., Kim, H. J., Van Der Helm, M. W., Segerink, L. I., Frimat, J. P., Hamilton, G. A., Ingber, D. E. & Van Den Berg, A., Feb 7 2015, In : Lab on a Chip. 15, 3, p. 745-752 8 p.

Research output: Contribution to journalArticle

Acoustic impedance
Microsystems
Electric Impedance
Microfluidics
Equipment and Supplies
2013
238 Citations (Scopus)

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation

Kim, H. J. & Ingber, D. E., Sep 1 2013, In : Integrative Biology (United Kingdom). 5, 9, p. 1130-1140 11 p.

Research output: Contribution to journalArticle

Caco-2 Cells
Monolayers
Pharmaceutical Preparations
Cytochrome P-450 CYP3A
Physiology
255 Citations (Scopus)

Microfabrication of human organs-on-chips

Huh, D., Kim, H. J., Fraser, J. P., Shea, D. E., Khan, M., Bahinski, A., Hamilton, G. A. & Ingber, D. E., Nov 8 2013, In : Nature Protocols. 8, 11, p. 2135-2157 23 p.

Research output: Contribution to journalArticle

Microtechnology
Microfabrication
Microfluidics
Endothelial cells
Biomimetics
2012
579 Citations (Scopus)

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

Kim, H. J., Huh, D., Hamilton, G. & Ingber, D. E., Jun 21 2012, In : Lab on a Chip. 12, 12, p. 2165-2174 10 p.

Research output: Contribution to journalArticle

Peristalsis
Intestines
Microfluidics
Lactobacillus rhamnosus
Physiology
2011
29 Citations (Scopus)

Complex function by design using spatially pre-structured synthetic microbial communities: Degradation of pentachlorophenol in the presence of Hg(ii)

Kim, H. J., Du, W. & Ismagilov, R. F., Feb 1 2011, In : Integrative Biology. 3, 2, p. 126-133 8 p.

Research output: Contribution to journalArticle

Pentachlorophenol
Degradation
Fibers
Ralstonia
Synthetic Biology
2009
72 Citations (Scopus)
Fluorescence In Situ Hybridization
Fluorescence
Cellulase
Slurries
Testing
4 Citations (Scopus)

Solubility-dependent melting temperature depression of binary substrate mixtures: A model study

Kim, H. J., Youn, S. H. & Shin, C. S., Feb 15 2009, In : Chemical Engineering Journal. 146, 3, p. 449-455 7 p.

Research output: Contribution to journalArticle

Melting point
solubility
Solubility
melting
substrate
2008
247 Citations (Scopus)

Defined spatial structure stabilizes a synthetic multispecies bacterial community

Hyun, J. K., Boedicker, J. Q., Jang, W. C. & Ismagilov, R. F., Nov 25 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 47, p. 18188-18193 6 p.

Research output: Contribution to journalArticle

Open Access
Lab-On-A-Chip Devices
Soil
Climate
Mouth
Theoretical Models
2007
54 Citations (Scopus)

Development of inhibitors against lipase and α-glucosidase from derivatives of monascus pigment

Kim, J. H., Kim, H. J., Park, H. W., Youn, S. H., Choi, D. Y. & Shin, C. S., Nov 1 2007, In : FEMS Microbiology Letters. 276, 1, p. 93-98 6 p.

Research output: Contribution to journalArticle

Monascus
Glucosidases
Lipase
Inhibitory Concentration 50
Norleucine
37 Citations (Scopus)

Development of lipase inhibitors from various derivatives of monascus pigment produced by Monascus fermentation

Kim, J. H., Kim, H. J., Kim, C., Jung, H., Kim, Y. O., Ju, J. Y. & Shin, C. S., Jan 1 2007, In : Food Chemistry. 101, 1, p. 357-364 8 p.

Research output: Contribution to journalArticle

Monascus
Lipase
Pigments
Fermentation
pigments
12 Citations (Scopus)

Lipase-catalyzed acylation of naringin with palmitic acid in highly concentrated homogeneous solutions

Youn, S. H., Kim, H. J., Kim, T. H. & Shin, C. S., May 2 2007, In : Journal of Molecular Catalysis B: Enzymatic. 46, 1-4, p. 26-31 6 p.

Research output: Contribution to journalArticle

Palmitic acid
Acylation
Palmitic Acid
Lipases
Lipase
2006
15 Citations (Scopus)

Lipase-catalyzed synthesis of sorbitol-fatty acid esters at extremely high substrate concentrations

Kim, H. J., Youn, S. H. & Shin, C. S., May 17 2006, In : Journal of Biotechnology. 123, 2, p. 174-184 11 p.

Research output: Contribution to journalArticle

Sorbitol
Lipases
Lipase
Fatty acids
Eutectics
9 Citations (Scopus)

Thermodynamic and morphological analysis of eutectic formation of CBZ-l-Asp and l-PheOMe·HCl mixtures

Kim, H. J., Kim, J. H., Youn, S. H. & Shin, C. S., Feb 15 2006, In : Thermochimica Acta. 441, 2, p. 168-175 8 p.

Research output: Contribution to journalArticle

eutectics
Eutectics
Thermodynamics
thermodynamics
Melting
2005
5 Citations (Scopus)

Eutectic formation analysis of amino acid mixtures using molecular dynamics simulations

Kim, H. J., Jong, H. K., Sung, H. Y. & Chul, S. S., Jul 1 2005, In : Biotechnology progress. 21, 4, p. 1307-1314 8 p.

Research output: Contribution to journalArticle

Molecular Dynamics Simulation
Methanol
Amino Acids
Freezing
Temperature
6 Citations (Scopus)

Optimization of enterokinase fermentation using a recombinant Saccharomyces cerevisiae

Kim, H. J., Kim, Y. H., Roh, Y. H., Seong, B. L. & Shin, C. S., Feb 1 2005, In : Process Biochemistry. 40, 2, p. 717-722 6 p.

Research output: Contribution to journalArticle

Enteropeptidase
Yeast
Fermentation
Saccharomyces cerevisiae
Ethanol
2003
8 Citations (Scopus)

Stereoselective enzymatic synthesis of an aspartame precursor of N-CBZ-L-Asp-L-PheOMe

Shin, G. H., Kim, C., Kim, H. J. & Shin, C. S., Dec 1 2003, In : Journal of Molecular Catalysis B: Enzymatic. 26, 3-6, p. 201-208 8 p.

Research output: Contribution to journalArticle

Aspartame
Peptide Hydrolases
Enzymes
Bacilli
Eutectics
2002
50 Citations (Scopus)

Morphology control of Monascus cells and scale-up of pigment fermentation

Kim, H. J., Kim, J. H., Oh, H. J. & Shin, C. S., Dec 31 2002, In : Process Biochemistry. 38, 5, p. 649-655 7 p.

Research output: Contribution to journalArticle

Monascus
Mycelium
Pigments
Fermentation
Seeds
1999
7 Citations (Scopus)

Conversion of D-sorbitol to L-sorbose by Gluconobacter suboxydans cells co-immobilized with oxygen-carriers in alginate beads

Jung Kim, H., Hyun Kim, J. & Soo Shin, C., Nov 1 1999, In : Process Biochemistry. 35, 3-4, p. 243-248 6 p.

Research output: Contribution to journalArticle

Gluconobacter
Sorbose
Immobilized Cells
Sorbitol
Alginate