John Powers, PhD

Assistant Professor

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  • 9 Similar Profiles
MicroRNAs Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
DNA Damage Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Ataxia Telangiectasia Medicine & Life Sciences
Epithelial-Mesenchymal Transition Medicine & Life Sciences

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Research Output 2002 2017

28 Citations (Scopus)

LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency

Tsanov, K. M., Pearson, D. S., Wu, Z., Han, A., Triboulet, R., Seligson, M. T., Powers, J. T., Osborne, J. K., Kane, S., Gygi, S. P., Gregory, R. I. & Daley, G. Q., Jan 1 2017, In : Nature Cell Biology. 19, 1, p. 60-67 8 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
RNA-Binding Proteins
Protein Biosynthesis
25 Citations (Scopus)

The LIN28B/let-7 axis is a novel therapeutic pathway in multiple myeloma

Manier, S., Powers, J. T., Sacco, A., Glavey, S. V., Huynh, D., Reagan, M. R., Salem, K. Z., Moschetta, M., Shi, J., Mishima, Y., Roche-Lestienne, C., Leleu, X., Roccaro, A. M., Daley, G. Q. & Ghobrial, I. M., Apr 1 2017, In : Leukemia. 31, 4, p. 853-860 8 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Clustered Regularly Interspaced Short Palindromic Repeats
RNA Sequence Analysis
79 Citations (Scopus)

Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma

Powers, J. T., Tsanov, K. M., Pearson, D. S., Roels, F., Spina, C. S., Ebright, R., Seligson, M., De Soysa, Y., Cahan, P., Theißen, J., Tu, H. C., Han, A., Kurek, K. C., Lapier, G. S., Osborne, J. K., Ross, S. J., Cesana, M., Collins, J. J., Berthold, F. & Daley, G. Q., Jan 1 2016, In : NATURE. 535, 7611, p. 246-251 6 p.

Research output: Contribution to journalArticle

Cell Line
92 Citations (Scopus)

Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models

Nguyen, L. H., Robinton, D. A., Seligson, M. T., Wu, L., Li, L., Rakheja, D., Comerford, S. A., Ramezani, S., Sun, X., Parikh, M. S., Yang, E. H., Powers, J. T., Shinoda, G., Shah, S. P., Hammer, R. E., Daley, G. Q. & Zhu, H., Aug 11 2014, In : Cancer Cell. 26, 2, p. 248-261 14 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Tumor Burden
RNA-Binding Proteins
45 Citations (Scopus)

The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming

Unternaehrer, J. J., Zhao, R., Kim, K., Cesana, M., Powers, J. T., Ratanasirintrawoot, S., Onder, T., Shibue, T., Weinberg, R. A. & Daley, G. Q., Jan 1 2014, In : Stem Cell Reports. 3, 5, p. 691-698 8 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Stem cells