Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma: Updates on Classification and Management

Teo Soleymani, Sumaira Z. Aasi, Roberto Novoa, S. Tyler Hollmig

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Atypical fibroxanthoma and undifferentiated pleomorphic sarcoma, or pleomorphic dermal sarcoma, are rare malignant cutaneous neoplasms existing along a clinicopathologic spectrum. Although these tumors share many similarities, recognition of distinguishing characteristics may predict differences in clinical behavior and outcomes. Salient features defining atypical fibroxanthoma include superficial tumors with minimal high-risk histologic features. Deeper tumors with high-risk histologic features are often clinically aggressive and should be appropriately designated as pleomorphic dermal sarcoma. Surgery remains gold standard in management; tumor extirpation with complete margin control is critical. In the high-risk tumor cohort, comprehensive evaluation and multidisciplinary management is paramount for optimal outcomes.

Original languageEnglish (US)
Pages (from-to)253-259
Number of pages7
JournalDermatologic Clinics
Volume37
Issue number3
DOIs
StatePublished - Jul 2019

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Sarcoma
Skin
Neoplasms
Skin Neoplasms

Keywords

  • Atypical fibroxanthoma
  • Cancer
  • Malignant fibrous histiocytoma
  • Micrographic surgery
  • Mohs
  • Pleomorphic dermal sarcoma
  • Sarcoma
  • Undifferentiated pleomorphic sarcoma

ASJC Scopus subject areas

  • Dermatology

Cite this

Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma : Updates on Classification and Management. / Soleymani, Teo; Aasi, Sumaira Z.; Novoa, Roberto; Hollmig, S. Tyler.

In: Dermatologic Clinics, Vol. 37, No. 3, 07.2019, p. 253-259.

Research output: Contribution to journalReview article

Soleymani, Teo ; Aasi, Sumaira Z. ; Novoa, Roberto ; Hollmig, S. Tyler. / Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma : Updates on Classification and Management. In: Dermatologic Clinics. 2019 ; Vol. 37, No. 3. pp. 253-259.
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