Enhancing efficiency and scientific impact of a clinical trials network: The Pediatric Heart Network Integrated CARdiac Data and Outcomes (iCARD) Collaborative

Sara K. Pasquali, Jonathan R. Kaltman, J. William Gaynor, Brian W. McCrindle, Jane W. Newburger, Brett R. Anderson, Mark A. Scheurer, Nelangi M. Pinto, Jeffrey B. Anderson, Matthew E. Oster, Jeffrey P. Jacobs, Bradley S. Marino, Carlos M. Mery, Gail D. Pearson

Research output: Contribution to journalArticle

Abstract

Recent years have seen an exponential increase in the variety of healthcare data captured across numerous sources. However, mechanisms to leverage these data sources to support scientific investigation have remained limited. In 2013 the Pediatric Heart Network (PHN), funded by the National Heart, Lung, and Blood Institute, developed the Integrated CARdiac Data and Outcomes (iCARD) Collaborative with the goals of leveraging available data sources to aid in efficiently planning and conducting PHN studies; supporting integration of PHN data with other sources to foster novel research otherwise not possible; and mentoring young investigators in these areas. This review describes lessons learned through the development of iCARD, initial efforts and scientific output, challenges, and future directions. This information can aid in the use and optimisation of data integration methodologies across other research networks and organisations.

Original languageEnglish (US)
Pages (from-to)1121-1126
Number of pages6
JournalCardiology in the young
Volume29
Issue number9
DOIs
StatePublished - Sep 1 2019

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Clinical Trials
Pediatrics
National Heart, Lung, and Blood Institute (U.S.)
Research
Research Personnel
Organizations
Delivery of Health Care
Mentoring
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Keywords

  • CHD
  • database
  • outcomes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine

Cite this

Pasquali, S. K., Kaltman, J. R., Gaynor, J. W., McCrindle, B. W., Newburger, J. W., Anderson, B. R., ... Pearson, G. D. (2019). Enhancing efficiency and scientific impact of a clinical trials network: The Pediatric Heart Network Integrated CARdiac Data and Outcomes (iCARD) Collaborative. Cardiology in the young, 29(9), 1121-1126. https://doi.org/10.1017/S104795111900163X

Enhancing efficiency and scientific impact of a clinical trials network : The Pediatric Heart Network Integrated CARdiac Data and Outcomes (iCARD) Collaborative. / Pasquali, Sara K.; Kaltman, Jonathan R.; Gaynor, J. William; McCrindle, Brian W.; Newburger, Jane W.; Anderson, Brett R.; Scheurer, Mark A.; Pinto, Nelangi M.; Anderson, Jeffrey B.; Oster, Matthew E.; Jacobs, Jeffrey P.; Marino, Bradley S.; Mery, Carlos M.; Pearson, Gail D.

In: Cardiology in the young, Vol. 29, No. 9, 01.09.2019, p. 1121-1126.

Research output: Contribution to journalArticle

Pasquali, SK, Kaltman, JR, Gaynor, JW, McCrindle, BW, Newburger, JW, Anderson, BR, Scheurer, MA, Pinto, NM, Anderson, JB, Oster, ME, Jacobs, JP, Marino, BS, Mery, CM & Pearson, GD 2019, 'Enhancing efficiency and scientific impact of a clinical trials network: The Pediatric Heart Network Integrated CARdiac Data and Outcomes (iCARD) Collaborative', Cardiology in the young, vol. 29, no. 9, pp. 1121-1126. https://doi.org/10.1017/S104795111900163X
Pasquali, Sara K. ; Kaltman, Jonathan R. ; Gaynor, J. William ; McCrindle, Brian W. ; Newburger, Jane W. ; Anderson, Brett R. ; Scheurer, Mark A. ; Pinto, Nelangi M. ; Anderson, Jeffrey B. ; Oster, Matthew E. ; Jacobs, Jeffrey P. ; Marino, Bradley S. ; Mery, Carlos M. ; Pearson, Gail D. / Enhancing efficiency and scientific impact of a clinical trials network : The Pediatric Heart Network Integrated CARdiac Data and Outcomes (iCARD) Collaborative. In: Cardiology in the young. 2019 ; Vol. 29, No. 9. pp. 1121-1126.
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