Gender specific considerations in atrial fibrillation treatment: a review

Sanghamitra Mohanty, Chintan Trivedi, Carola Gianni, Andrea Natale

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Introduction: Distinct differences in clinical presentation, utilization of therapy and outcome of atrial fibrillation (AF) management are observed in men vs women. This review focuses on our current knowledge on these sex-specific variations and how those impact the detection of AF and therapeutic decisions. Areas covered: The current article reviews reports illustrating gender-related differences in the incidence, prevalence, clinical presentations, different risk factors, pathophysiology, therapeutic strategies, procedural parameters in catheter ablation for AF and complications and long-term outcome of ablative therapy including arrhythmia recurrence and quality of life. Some of these areas have been investigated widely providing conclusive evidences, whereas others have many unanswered questions or conflicting findings that need clarifications. Expert opinion: Attainment of sinus rhythm and healthy quality of life as well as prevention of complications, especially stroke, are the main goals of AF management. Sex-specific variations are evident in many areas in the spectrum of AF that should be addressed by large population-based or randomized trials to facilitate customization of AF-therapy to maximize success in both genders.

Original languageEnglish (US)
Pages (from-to)365-374
Number of pages10
JournalExpert Opinion on Pharmacotherapy
Volume19
Issue number4
DOIs
StatePublished - Mar 4 2018

Fingerprint

Atrial Fibrillation
Therapeutics
Quality of Life
Catheter Ablation
Expert Testimony
Cardiac Arrhythmias
Stroke
Recurrence
Incidence
Population

Keywords

  • Atrial fibrillation
  • ablation-outcome
  • catheter ablation
  • gender

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Gender specific considerations in atrial fibrillation treatment : a review. / Mohanty, Sanghamitra; Trivedi, Chintan; Gianni, Carola; Natale, Andrea.

In: Expert Opinion on Pharmacotherapy, Vol. 19, No. 4, 04.03.2018, p. 365-374.

Research output: Contribution to journalReview article

Mohanty, Sanghamitra ; Trivedi, Chintan ; Gianni, Carola ; Natale, Andrea. / Gender specific considerations in atrial fibrillation treatment : a review. In: Expert Opinion on Pharmacotherapy. 2018 ; Vol. 19, No. 4. pp. 365-374.
@article{86d1162b72ea4e028312cf55ff37adc4,
title = "Gender specific considerations in atrial fibrillation treatment: a review",
abstract = "Introduction: Distinct differences in clinical presentation, utilization of therapy and outcome of atrial fibrillation (AF) management are observed in men vs women. This review focuses on our current knowledge on these sex-specific variations and how those impact the detection of AF and therapeutic decisions. Areas covered: The current article reviews reports illustrating gender-related differences in the incidence, prevalence, clinical presentations, different risk factors, pathophysiology, therapeutic strategies, procedural parameters in catheter ablation for AF and complications and long-term outcome of ablative therapy including arrhythmia recurrence and quality of life. Some of these areas have been investigated widely providing conclusive evidences, whereas others have many unanswered questions or conflicting findings that need clarifications. Expert opinion: Attainment of sinus rhythm and healthy quality of life as well as prevention of complications, especially stroke, are the main goals of AF management. Sex-specific variations are evident in many areas in the spectrum of AF that should be addressed by large population-based or randomized trials to facilitate customization of AF-therapy to maximize success in both genders.",
keywords = "Atrial fibrillation, ablation-outcome, catheter ablation, gender",
author = "Sanghamitra Mohanty and Chintan Trivedi and Carola Gianni and Andrea Natale",
year = "2018",
month = "3",
day = "4",
doi = "10.1080/14656566.2018.1434144",
language = "English (US)",
volume = "19",
pages = "365--374",
journal = "Expert Opinion on Pharmacotherapy",
issn = "1465-6566",
publisher = "Informa Healthcare",
number = "4",

}

TY - JOUR

T1 - Gender specific considerations in atrial fibrillation treatment

T2 - a review

AU - Mohanty, Sanghamitra

AU - Trivedi, Chintan

AU - Gianni, Carola

AU - Natale, Andrea

PY - 2018/3/4

Y1 - 2018/3/4

N2 - Introduction: Distinct differences in clinical presentation, utilization of therapy and outcome of atrial fibrillation (AF) management are observed in men vs women. This review focuses on our current knowledge on these sex-specific variations and how those impact the detection of AF and therapeutic decisions. Areas covered: The current article reviews reports illustrating gender-related differences in the incidence, prevalence, clinical presentations, different risk factors, pathophysiology, therapeutic strategies, procedural parameters in catheter ablation for AF and complications and long-term outcome of ablative therapy including arrhythmia recurrence and quality of life. Some of these areas have been investigated widely providing conclusive evidences, whereas others have many unanswered questions or conflicting findings that need clarifications. Expert opinion: Attainment of sinus rhythm and healthy quality of life as well as prevention of complications, especially stroke, are the main goals of AF management. Sex-specific variations are evident in many areas in the spectrum of AF that should be addressed by large population-based or randomized trials to facilitate customization of AF-therapy to maximize success in both genders.

AB - Introduction: Distinct differences in clinical presentation, utilization of therapy and outcome of atrial fibrillation (AF) management are observed in men vs women. This review focuses on our current knowledge on these sex-specific variations and how those impact the detection of AF and therapeutic decisions. Areas covered: The current article reviews reports illustrating gender-related differences in the incidence, prevalence, clinical presentations, different risk factors, pathophysiology, therapeutic strategies, procedural parameters in catheter ablation for AF and complications and long-term outcome of ablative therapy including arrhythmia recurrence and quality of life. Some of these areas have been investigated widely providing conclusive evidences, whereas others have many unanswered questions or conflicting findings that need clarifications. Expert opinion: Attainment of sinus rhythm and healthy quality of life as well as prevention of complications, especially stroke, are the main goals of AF management. Sex-specific variations are evident in many areas in the spectrum of AF that should be addressed by large population-based or randomized trials to facilitate customization of AF-therapy to maximize success in both genders.

KW - Atrial fibrillation

KW - ablation-outcome

KW - catheter ablation

KW - gender

UR - http://www.scopus.com/inward/record.url?scp=85043523963&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85043523963&partnerID=8YFLogxK

U2 - 10.1080/14656566.2018.1434144

DO - 10.1080/14656566.2018.1434144

M3 - Review article

C2 - 29424249

AN - SCOPUS:85043523963

VL - 19

SP - 365

EP - 374

JO - Expert Opinion on Pharmacotherapy

JF - Expert Opinion on Pharmacotherapy

SN - 1465-6566

IS - 4

ER -