Myeloid sarcoma involving the testis

Jose R. Valbuena, Joan Admirand, Pei Lin, L. Jeffrey Medeiros

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Myeloid sarcoma is a neoplasm of immature granulocytes, monocytes, or both involving any extramedullary site. Myeloid sarcoma involving the testis, however, is uncommon and very rarely occurs as an isolated mass. We describe 4 patients with myeloid sarcoma involving the testis, including 2 patients in whom the neoplasm was isolated to the testis (1 unilateral and 1 bilateral). Histologically, 4 neoplasms were poorly differentiated and 1 was blastic. Each neoplasm was shown to be of myeloid lineage, and negative for T- and B-cell specific antigens using immunohistochemical methods. One case was also positive for chloroacetate esterase. In the literature, most cases of myeloid sarcoma involving the testis represent relapse or the initial presentation of acute myeloid leukemia. Including the 2 cases we report here, only 7 cases of myeloid sarcoma isolated to the testis have been reported.

Original languageEnglish (US)
Pages (from-to)445-452
Number of pages8
JournalAmerican Journal of Clinical Pathology
Volume124
Issue number3
DOIs
StatePublished - Jan 1 2005

Fingerprint

Myeloid Sarcoma
Testis
Neoplasms
Granulocytes
Acute Myeloid Leukemia
Monocytes
B-Lymphocytes
Antigens
Recurrence

Keywords

  • Acute myeloid leukemia
  • Immunohistochemistry
  • Myeloid sarcoma
  • Testis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Myeloid sarcoma involving the testis. / Valbuena, Jose R.; Admirand, Joan; Lin, Pei; Medeiros, L. Jeffrey.

In: American Journal of Clinical Pathology, Vol. 124, No. 3, 01.01.2005, p. 445-452.

Research output: Contribution to journalArticle

Valbuena, Jose R. ; Admirand, Joan ; Lin, Pei ; Medeiros, L. Jeffrey. / Myeloid sarcoma involving the testis. In: American Journal of Clinical Pathology. 2005 ; Vol. 124, No. 3. pp. 445-452.
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