Quantifying Movement in Preterm Infants Using Photoplethysmography

Ian Zuzarte, Premananda Indic, Dagmar Sternad, David Paydarfar

Research output: Contribution to journalArticle

Abstract

Long-term recordings of movement in preterm infants might reveal important clinical information. However, measurement of movement is limited because of time-consuming and subjective analysis of video or reluctance to attach additional sensors to the infant. We evaluated whether photoplethysmogram (PPG), routinely used for oximetry in preterm infants in the neonatal intensive care unit (NICU), can provide reliable long-term measurements of movement. In 18 infants [mean post-conceptional age (PCA) 31.10 weeks, range 29–34.29 weeks], we designed and tested a wavelet-based algorithm that detects movement signals from the PPG. The algorithm’s performance was optimized relative to subjective assessments of movement using video and accelerometers attached to two limbs and force sensors embedded within the mattress (five infants, three raters). We then applied the optimized algorithm to infants receiving routine care in the NICU without additional sensors. The algorithm revealed a decline in brief movements (< 5 s) with increasing PCA (13 infants, r = − 0.87, p < 0.001, PCA range 27.3–33.9 weeks). Our findings suggest that quantitative relationships between motor activity and clinical outcomes in preterm infants can be studied using routine photoplethysmography.

Original languageEnglish (US)
Pages (from-to)646-658
Number of pages13
JournalAnnals of Biomedical Engineering
Volume47
Issue number2
DOIs
StatePublished - Feb 15 2019

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Photoplethysmography
Intensive care units
Sensors
Accelerometers

Keywords

  • Continuous wavelet transform
  • Motor development
  • Movement detection
  • Photoplethysmography
  • Preterm movement

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Quantifying Movement in Preterm Infants Using Photoplethysmography. / Zuzarte, Ian; Indic, Premananda; Sternad, Dagmar; Paydarfar, David.

In: Annals of Biomedical Engineering, Vol. 47, No. 2, 15.02.2019, p. 646-658.

Research output: Contribution to journalArticle

Zuzarte, Ian ; Indic, Premananda ; Sternad, Dagmar ; Paydarfar, David. / Quantifying Movement in Preterm Infants Using Photoplethysmography. In: Annals of Biomedical Engineering. 2019 ; Vol. 47, No. 2. pp. 646-658.
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