Successful use of the 308-nm excimer laser in early patch stage mycosis fungoides

Andrew M. Armenta, Krystal M. Jones, Jason S. Reichenberg

Research output: Contribution to journalArticle

Abstract

Introduction: Mycosis fungoides (MF), a type of cutaneous T-cell lymphoma, is a rare condition with a variety of treatment options. A frequently utilized method in the treatment of early-stage MF is phototherapy. Full body phototherapy can be associated with photoaging of the skin and an increased risk of developing skin cancer. Targeted phototherapy, with a 308-nm excimer laser, may be just as effective and of a lower risk. This makes it especially useful in the treatment of patients with dysplastic nevi (DN) or other conditions which can put them at a higher risk of developing skin cancer. There are currently limited data on the treatment of early-stage MF with an excimer laser. Case Report: This study reports on a 43-year-old female patient presented to the clinic with early-stage (Ia) MF. Given her history of DN, she wished to pursue targeted phototherapy with an excimer laser. Localized light treatment was performed via a 308-nm excimer laser, 3 times weekly, for a total of 17 treatments to affected lesions. Following excimer laser treatment, she had a clinical resolution of her patches. On the follow-up clinic visits, she maintained her excellent response 12 months out. Conclusion: Targeted phototherapy with a 308-nm excimer laser may be a safer and equally effective alternative to generalized phototherapy in the treatment of early-stage MF. This case report demonstrates its efficacy and advantages over traditional generalized phototherapy.

Original languageEnglish (US)
Pages (from-to)251-253
Number of pages3
JournalJournal of Lasers in Medical Sciences
Volume10
Issue number3
DOIs
StatePublished - Jan 1 2019

Fingerprint

Excimer Lasers
Mycosis Fungoides
Phototherapy
Dysplastic Nevus Syndrome
Skin Neoplasms
Therapeutics
Skin Aging
Cutaneous T-Cell Lymphoma
Ambulatory Care
Light

Keywords

  • Excimer
  • Lasers
  • Mycosis fungoides

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine
  • Dentistry (miscellaneous)
  • Dermatology
  • Nephrology
  • Urology

Cite this

Successful use of the 308-nm excimer laser in early patch stage mycosis fungoides. / Armenta, Andrew M.; Jones, Krystal M.; Reichenberg, Jason S.

In: Journal of Lasers in Medical Sciences, Vol. 10, No. 3, 01.01.2019, p. 251-253.

Research output: Contribution to journalArticle

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